Teen ankle sprain study: which rehab approach works best?

NCT ID NCT07287020

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at two ways to help teenagers recover from a first-time ankle sprain. One group used the traditional PRICE method (rest, ice, compression, elevation) plus ibuprofen. The other group used a newer approach called PEACE and LOVE, which avoids anti-inflammatory drugs and focuses on movement and education. Researchers measured ankle strength and balance over 12-15 weeks in 76 teens aged 12-17 to see which method led to better recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PRICE protocol (Protection, Rest, Ice, Compression, Elevation) plus ibuprofen, and PEACE and LOVE protocol (Protection, Elevation, Avoid anti-inflammatories, Compression, Education, Load, Optimism, Vascularization, Exercise)

What this could lead to

If one approach proves better, it could guide how teens recover from ankle sprains more effectively, potentially reducing long-term weakness or balance issues.

What could go wrong

This is a small, single-center study with only 76 participants. Results may not apply to all teens or more severe injuries. The study is completed, so no new data is coming.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ankle injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lithuanian University of Health Sciences

    Kaunas, LT-44307, Lithuania