Scientists uncover hidden foot muscle changes after ankle sprains

NCT ID NCT05815576

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how foot and ankle joints move and bear weight during running in people with chronic ankle instability, those who recovered from a sprain, and healthy individuals. Researchers used cameras and pressure plates to measure joint angles and forces, and ultrasound to check foot muscle size. The goal was to understand why some people develop long-term instability after an ankle sprain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intrinsic foot muscle fatigue via electrostimulation

What this could lead to

If successful, this could help design better rehabilitation programs for people with chronic ankle instability.

What could go wrong

This is a small, completed observational study with no treatment being tested, so it won't directly lead to a new therapy. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ankle injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UZ Leuven, Pellenberg

    Lubbeek, B-3212, Belgium