New study targets the 'Blahs' in depressed teens

NCT ID NCT05487885

First seen Apr 04, 2026 · Last updated Apr 30, 2026 · Updated 3 times

Summary

This study looked at anhedonia—a lack of interest or pleasure in activities—in 123 young people with depression. Participants completed brain scans, blood tests, and surveys to measure symptoms. Some also tried treatments like brain stimulation (TMS), positive thinking exercises, or ketamine. The goal was to better understand anhedonia and find new ways to help people whose depression doesn't improve with standard treatments.

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Contacts and locations

Locations

  • Loeffler Building

    Pittsburgh, Pennsylvania, 15213, United States

Conditions

Explore the condition pages connected to this study.