Which anesthesia gets you home faster after knee surgery?
NCT ID NCT07672301
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares general anesthesia (given through an IV) with spinal anesthesia (a numbing shot in the back) for people having a knee replacement. The goal is to see which approach allows more patients to go home the same day. Researchers will also track recovery, pain, nausea, and thinking skills after surgery. About 150 adults are being enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
propofol, dexmedetomidine, fentanyl, hydromorphone, mepivacaine
What this could lead to
If it works, this could help doctors choose the best anesthesia for faster recovery and same-day discharge after knee replacement.
What could go wrong
This is an early-phase study with only 150 participants, so results may not apply to everyone. The main goal is comparing discharge rates, not curing disease.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for TOTAL KNEE ARTHROPLASTY (TKA) are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact