New pill could cut transfusions for thalassemia patients

NCT ID NCT06302491

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 study tests an oral drug called AND017 in 64 people with β-thalassemia, a blood disorder that often requires regular transfusions. Half the participants get the drug, half get a placebo, and everyone continues standard care. The goal is to see if AND017 is safe and can raise hemoglobin levels, potentially reducing transfusion needs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AND017 capsules

What this could lead to

If successful, AND017 could reduce the need for blood transfusions in people with β-thalassemia by boosting hemoglobin levels.

What could go wrong

This is an early Phase 2 trial with only 64 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

beta thalassemia hemoglobin E-beta-thalassemia syndrome sickle cell-beta-thalassemia disease syndrome thalassemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guangxi Medical University No.1 Affiliated Hospital

    RECRUITING

    Nanning, Guangxi, 530021, China

    Contact

  • Hainan General Hospital

    RECRUITING

    Haikou, Hainan, 570203, China

    Contact

  • Liuzhou People's Hospital

    RECRUITING

    Liuzhou, Guangxi, 545006, China

    Contact

  • Maoming People's Hospital

    RECRUITING

    Maoming, Guangdong, 525000, China

    Contact

  • Nanfang Hospital Southern Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510515, China

    Contact