New hope for ALS? experimental drug AMX0114 enters human testing
NCT ID NCT06665165
First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 21 times
Summary
This early-stage study tests an experimental drug, AMX0114, in 48 adults with ALS. The main goal is to check if the drug is safe and tolerable. Researchers will also measure how the drug moves through the body. This is a first step to see if the drug might help control the disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alliance for Multispecialty Research, LLC
RECRUITINGKnoxville, Tennessee, 37909, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Georgetown University Hospital Pasquerilla Healthcare Center
RECRUITINGWashington D.C., District of Columbia, 20007, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Houston Methodist Neurological Institute
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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London Health Sciences Centre
RECRUITINGLondon, Ontario, N6G 2M3, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital, Healey & AMG Center for ALS
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Mayo Clinic in Florida
RECRUITINGJacksonville, Florida, 32224, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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McGill University Health Centre - Centre for Innovative Medicine
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
Contact
Contact Email: •••••@•••••
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McMaster University
RECRUITINGHamilton, Ontario, L8N 3Z5, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orlando Regional Medical Center, Orlando Health Neuroscience Institute
RECRUITINGOrlando, Florida, 32806, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Temple University of the Commonwealth System of Higher Education
RECRUITINGPhiladelphia, Pennsylvania, 19140, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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University of Calgary
RECRUITINGCalgary, Alberta, T2N 4Z6, Canada
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California, San Diego
RECRUITINGLa Jolla, California, 92093, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida
RECRUITINGGainesville, Florida, 32611, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.