New tool successfully delivers heart hole plugs in 254 patients

NCT ID NCT04433520

First seen Mar 23, 2026 · Last updated May 16, 2026 · Updated 10 times

Summary

This study tested a new delivery system (Amplatzer Trevisio) used to implant devices that close holes in the heart. It involved 254 people with conditions like PFO or ASD. The system worked well, successfully deploying the devices, and safety was monitored for serious side effects like heart perforation or device movement.

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Contacts and locations

Locations

  • Amsterdam Academic Medical Centre (AMC)

    Amsterdam, 1105 AZ, Netherlands

  • Azienda Ospedaliera Monaldi

    Naples, 80131, Italy

  • CHRU Lille

    Lille, 59037, France

  • CHU Gabriel Montpied

    Clermont-Ferrand, 63003, France

  • CHU Hopital G. & R. Laënnec

    Nantes, 44093, France

  • CHU Trousseau

    Chambray-lès-Tours, 37170, France

  • Centre Médico Chirurgical Marie Lannelongue

    Le Plessis-Robinson, 92350, France

  • Deutsches Herzzentrum Berlin

    Berlin, 13353, Germany

  • Deutsches Herzzentrum München des Freistaates Bayern

    München, 80636, Germany

  • Fondazione Toscana Gabriele Monasterio Via Aurelia Sud

    Massa, Tuscany, 54100, Italy

  • Gornoslaskie Centrum Medyczne im.prof. Leszka Gieca ul.

    Katowice, Silesian Voivodeship, 40-635, Poland

  • Herz- und Diabeteszentrum NRW

    Bad Oeynhausen, 32545, Germany

  • Hopital Haut Leveque

    Pessac, 33604, France

  • Hopital d'adulte de la Timone

    Marseille, 13005, France

  • Hospital Universitario Reina Sofia

    Córdoba, 14004, Spain

  • Hospital Universitario de la Paz

    Madrid, 28046, Spain

  • Hospital Universitario de la Paz - Pediatrico

    Madrid, 28046, Spain

  • Policlinico San Donato

    San Donato Milanese, 20097, Italy

  • Stadtspital Triemli

    Zurich, 8063, Switzerland

  • The Cardinal Stefan Wyszynski Institute of Cardiology

    Warsaw, 04-628, Poland

  • Universitätsklinikum Schleswig-Holstein Campus Kiel

    Kiel, 24105, Germany

  • Uniwersytekie Centrum Kliniczne

    Gdansk, 80-952, Poland

Conditions

Explore the condition pages connected to this study.