Heart device under surveillance: 500 patients tracked for safety

NCT ID NCT04349995

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 500 people who received the Amplatzer PFO Occluder, a device that closes a small hole in the heart called PFO. Researchers tracked serious complications within 30 days and longer-term issues like stroke or blood clots over 3 years. The goal was to confirm the device is safe and works as intended.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Amplatzer PFO Occluder (a device implanted to close a hole in the heart)

What this could lead to

If successful, this confirms the device is safe and effective for closing PFO, potentially reducing stroke risk in certain patients.

What could go wrong

This is an observational study, not a randomized trial, so results may not prove the device is better than no treatment. Risks include device-related complications like blood clots or irregular heartbeat.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

patent foramen ovale

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Abbott Medical Japan LLC

    Mita, Minato, 108-6304, Japan