Headband device could spot hidden shunts without needles

NCT ID NCT07414446

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a head-worn ultrasound device called SONAS that listens for bubble signals in the brain during a standard heart ultrasound. It aims to see if the device can accurately detect right-to-left shunts—abnormal connections between blood vessels—in adults with hereditary hemorrhagic telangiectasia (HHT). Participants wear the headband while getting a routine bubble echo test, and the device's readings are compared to the standard test results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial Ultrasound Device (SONAS)
What this could lead to
If successful, this device could offer a simpler, non-invasive way to detect and distinguish heart vs. lung shunts, potentially reducing the need for more invasive tests.
What could go wrong
This is a small, early-stage study (40 participants) focused on diagnostic accuracy. The device may not prove reliable enough to replace standard methods, and results may not apply to broader populations.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • St. Antonius Hospital

    RECRUITING

    Nieuwegein, Utrecht, 3435CM, Netherlands

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