Can a stem-cell wrap boost nerve repair after carpal tunnel surgery?

NCT ID NCT07723313

First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This trial tests whether placing a piece of amniotic membrane soaked in a stem-cell-derived solution (secretome) on the nerve during carpal tunnel release surgery can improve symptom relief and nerve function. Adults with moderate-to-severe carpal tunnel syndrome that hasn't improved with conservative care will be randomly assigned to standard surgery alone or surgery plus the membrane and secretome. Outcomes are measured at 3 weeks using a hand-function questionnaire and nerve-conduction tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
amniotic membrane and secretome (stem-cell-derived solution) applied to the nerve during surgery
What this could lead to
If it works, this could point toward a simple add-on treatment to improve nerve recovery and reduce symptoms after carpal tunnel surgery.
What could go wrong
This is a very early, small trial with only 30 participants, so results may not apply widely. The added step may not improve outcomes over standard surgery alone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Prof. dr. I.G.N.G. Ngoerah General Hospital

    RECRUITING

    Denpasar, Bali, 80113, Indonesia

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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