New hope for kids with down syndrome and leukemia: gentler chemo shows promise

NCT ID NCT07232134

First seen Nov 18, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study tests a chemotherapy plan designed specifically for children (0-18 years) with acute myeloid leukemia (AML) and Down syndrome. The goal is to improve survival while reducing harsh side effects by using lower drug doses. About 100 children in Russia will receive four rounds of chemo, and researchers will track how well they respond and how safe the treatment is.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National medical research center of pediatric haematology, oncology and immulogy named after Dmytriy Rogachyov, Moscow, 117198

    RECRUITING

    Moscow, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.