Federal Research Institute Of Pediatric Hematology, Oncology And Immunology

This study aims to prevent graft-versus-host disease (GVHD) in children with high-risk or relapsed blood cancers who receive a stem cell transplant from a half-matched donor. Researchers will add special regulatory immune cells to the donor cells to reduce the risk of GVHD while …

This study tests a chemotherapy plan designed specifically for children (0-18 years) with acute myeloid leukemia (AML) and Down syndrome. The goal is to improve survival while reducing harsh side effects by using lower drug doses. About 100 children in Russia will receive four ro…

This study tests whether giving special immune cells (NK cells) before and after a stem cell transplant can help prevent leukemia from coming back in children and young adults (ages 0–25) with acute leukemia that is hard to treat or has leftover disease. The NK cells are grown in…

This study tests a new treatment for children with high-risk neuroblastoma that has not responded to standard therapy or has come back. The approach combines chemotherapy, immunotherapy, and the patient's own natural killer (NK) cells to help the immune system fight the cancer mo…