New shot form of cancer drug tested in advanced tumors

NCT ID NCT04606381

First seen Nov 01, 2025 · Last updated May 26, 2026 · Updated 29 times

Summary

This study tests a new way to give the cancer drug amivantamab as a shot under the skin instead of through an IV. It includes 158 adults with advanced solid tumors that may respond to this type of treatment. The main goals are to check safety and find the best dose for the shot form.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    West Hollywood, California, 90048, United States

  • Chungbuk National University Hospital

    Cheongju-si, 28644, South Korea

  • Community Health Network

    Indianapolis, Indiana, 46256, United States

  • Langone Health at NYC University, NYU School of Medicine

    New York, New York, 10016, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Royal Marsden Hospital

    Sutton, SM2 5PT, United Kingdom

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Seoul National University Bundang Hospital

    Seongnam-si, 13620, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • The Christie Nhs Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • University Health Network

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.