Could a simple shot replace IV drips for some cancer patients?

NCT ID NCT04606381

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 26 times

Summary

This early-stage study tests if amivantamab, a drug that targets certain cancer cells, can be given as a shot under the skin instead of through an IV. It includes 158 adults with advanced solid tumors like lung or head and neck cancer. The main goals are to check safety, find the right dose, and see how the body handles the drug.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cedars Sinai Medical Center

    West Hollywood, California, 90048, United States

  • Chungbuk National University Hospital

    Cheongju-si, 28644, South Korea

  • Community Health Network

    Indianapolis, Indiana, 46256, United States

  • Langone Health at NYC University, NYU School of Medicine

    New York, New York, 10016, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Royal Marsden Hospital

    Sutton, SM2 5PT, United Kingdom

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Seoul National University Bundang Hospital

    Seongnam-si, 13620, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • The Christie Nhs Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • University Health Network

    Toronto, Ontario, M5G 2M9, Canada

Conditions

Explore the condition pages connected to this study.