Old depression drug shows promise for bladder pain
NCT ID NCT00124306
First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 25 times
Summary
This study tested whether amitriptyline, a drug already used for depression and chronic pain, can relieve symptoms of painful bladder syndrome (also called interstitial cystitis). 271 newly diagnosed adults took part. The goal was to see if the drug reduces bladder pain and frequent urination. Results were measured by patient reports of symptom improvement after 12 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Henry Ford Hospital
Detroit, Michigan, 48202, United States
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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Queen's University
Kingston, Ontario, K7L 2Y7, Canada
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Stanford University Medical Center
Stanford, California, 94305, United States
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University of Iowa Hospitals and Clinic
Iowa City, Iowa, 52242, United States
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University of Maryland
Baltimore, Maryland, 21201, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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University of Rochester Medical Center
Rochester, New York, 14642, United States
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University of Washington
Seattle, Washington, 98195, United States
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William Beaumont Hospital
Royal Oak, Michigan, 48073, United States
Conditions
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