New gel for infected wounds enters first human test

NCT ID NCT07379684

Recruiting now Disease control Sponsor: Macro Biologics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This early-stage trial tests a new gel called Amicidin-β, applied directly into infected surgical or traumatic wounds during a procedure. The main goal is to see if it is safe and easy for surgeons to use. About 44 adults will take part, comparing standard care alone to standard care plus the gel.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Amicidin-β topical solution
What this could lead to: If safe, this could lead to a new treatment option for wound infections that is applied directly during surgery.
What could go wrong: This is a very early Phase 1 trial with only 44 people, so safety and effectiveness are not yet proven. It may not work in larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Surgical Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SURGICAL WOUND INFECTION TRAUMATIC WOUND INFECTION

Contacts and locations

Locations

LifeBridge Health
RECRUITING

Baltimore, Maryland, 21215, United States
Lundquist Institute
RECRUITING

Torrance, California, 90502, United States
Snake River Research, PLLC
RECRUITING

Idaho Falls, Idaho, 83404, United States
The Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Washington University in St. Louis
RECRUITING

St Louis, Missouri, 631110, United States

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