Early cancer drug trial halted after testing in just 3 patients

NCT ID NCT05317078

Summary

This was a very early, first-in-human study to test the safety and find the right dose of an experimental drug called AMG 794. It was for adults with advanced or spreading cancers that have a specific marker called Claudin 6 (CLDN6), including certain lung and ovarian cancers. The main goal was to see how much of the drug the body could handle and to check for side effects, but the trial was terminated after only 3 people were enrolled.

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Contacts and locations

Locations

  • Cabrini Hospital

    Malvern, Victoria, 3144, Australia

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Inselspital Bern

    Bern, 3010, Switzerland

  • Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • Southern Oncology Clinical Research Unit

    Bedford Park, South Australia, 5042, Australia

  • University of California Irvine

    Orange, California, 92868, United States

  • University of California Los Angeles

    Los Angeles, California, 90095-1678, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23219, United States

Conditions

Explore the condition pages connected to this study.