Early cancer drug trial halted after just 3 patients

NCT ID NCT05317078

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 25 times

Summary

This was a very early (Phase 1) study testing a new drug called AMG 794 in adults with advanced lung, ovarian, or other solid tumors that had a specific marker (claudin 6). The main goal was to check safety and find the right dose. The study was stopped early after only 3 people took part, so we don't have enough information to know if the drug works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cabrini Hospital

    Malvern, Victoria, 3144, Australia

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Inselspital Bern

    Bern, 3010, Switzerland

  • Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • Southern Oncology Clinical Research Unit

    Bedford Park, South Australia, 5042, Australia

  • University of California Irvine

    Orange, California, 92868, United States

  • University of California Los Angeles

    Los Angeles, California, 90095-1678, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23219, United States

Conditions

Explore the condition pages connected to this study.