New drug tested in patients with liver disease
NCT ID NCT07428525
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how the body processes a single dose of the drug AMG 133 in people with different levels of liver impairment compared to those with healthy livers. Thirty-six adults took part, and researchers measured drug levels in the blood and checked for side effects. The goal is to guide safe dosing for future studies in patients with liver disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AMG 133
What this could lead to
If successful, this study will help doctors understand how to dose AMG 133 safely in patients with liver disease.
What could go wrong
This is an early, small study (36 people) focused on drug levels, not on treating a disease. Results may not apply to broader populations.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Clinical Pharmacology Of Miami, LLC
Miami, Florida, 33172, United States
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Orlando Clinical Research Center
Orlando, Florida, 32809, United States
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Panax Clinical Research
Miami Lakes, Florida, 33014-2811, United States
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Pinnacle Clinical Research San Antonio
San Antonio, Texas, 78229-4801, United States
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The Texas Liver Institute, Inc.
San Antonio, Texas, 78215-2100, United States