New combo treatment tackles sun damage and precancerous lesions in one go

NCT ID NCT07053852

Completed Disease control Sponsor: Sherrif Ibrahim Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small study tested whether a gel called Ameluz, activated by a special broadband light (BBL), can treat both actinic keratoses (rough, scaly spots that can turn into skin cancer) and general sun damage on the face. Ten adults with mild to moderate skin damage received two treatments. Researchers measured how many spots cleared up and how much the skin's appearance improved after one and two months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ameluz (a gel applied to the skin) plus broad band light (BBL) therapy
What this could lead to: If it works, this could offer a single treatment that both clears precancerous skin spots and improves sun-damaged skin appearance.
What could go wrong: This is a very small, early Phase 1 trial with only 10 people. Results may not apply to everyone, and long-term safety or effectiveness is not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

actinic keratosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACTINIC KERATOSES PHOTODAMAGE

Contacts and locations

Locations

Rochester Dermatologic Surgery

Victor, New York, 14564, United States

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