Early amantadine may delay Parkinson's drug side effects
NCT ID NCT01538329
First seen Apr 07, 2026 · Last updated Apr 25, 2026 · Updated 5 times
Summary
This study tested whether giving amantadine early in Parkinson's disease treatment can prevent or delay the involuntary movements (dyskinesia) caused by the standard drug L-DOPA. 210 people with early-stage Parkinson's took either amantadine or a placebo for 18 months. The goal was to see if early use of amantadine could reduce the long-term risk of these movement problems.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CH Charles Nicolle
Rouen, 76031, France
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CH Jean Rougier
Cahors, 46005, France
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CH Montauban
Montauban, 82013, France
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CH de Narbonne
Narbonne, 11108, France
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CHG Aix en Provence
Aix-en-Provence, 13616, France
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CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
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CHU Dijon
Dijon, 21079, France
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CHU Dupuytren
Limoges, 87042, France
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CHU Lille
Lille, 59037, France
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CHU de Bordeaux
Bordeaux, 33604, France
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CHU de Strasbourg
Strasbourg, France
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CHU de Toulouse
Toulouse, 31000, France
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CHu de Nantes
Nantes, 44093, France
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Hopital Jean Bernard
Poitiers, 86021, France
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Hopital Lyon
Lyon, 69003, France
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Hopital de la Timone
Marseille, 13385, France
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Hopital pitié Salpétriére
Paris, 75013, France
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hopital Saint Eloi
Montpellier, 34295, France
Conditions
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