New pill aims to slow Alzheimer's before symptoms worsen

NCT ID NCT06402838

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental daily pill (RO7269162) in 256 people who either have brain plaques but no symptoms, or have mild memory problems due to Alzheimer's. Participants take the pill or a placebo for about 1.5 years, with regular check-ups to monitor safety and brain changes via PET scans and spinal fluid tests. The goal is to see if the drug can reduce harmful plaques and other disease markers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aarhus Universitetshospital Skejby

    Aarhus N, 8200, Denmark

  • Ambulates Gesundheitszentrum der Charité GmbH

    Berlin, 12200, Germany

  • CHU de Rouen Hopital

    Rouen, 76031, France

  • Centro de Investigación Clínica UC-CICUC

    Santiago, 8330034, Chile

  • Charing Cross Hospital

    London, W6 8RF, United Kingdom

  • Complejo Asistencial Universitario de Salamanca

    Salamaca, Salamanca, 37007, Spain

  • ECRC Experimental and Clinical Research Center, Charité Campus Berlin Buch, Memory Clinic

    Berlin, 13125, Germany

  • ETG Neuroscience Sp. z o.o.

    Warsaw, 02-777, Poland

  • EUROMEDIS Sp z o o

    Szczecin, 70-111, Poland

  • Fondazione Istituto Neurologico Mondino IRCCS

    Pavia, Lombardy, 27100, Italy

  • Fundacio ACE

    Barcelona, 08028, Spain

  • Gerontopole

    Toulouse, 31059, France

  • Groupement Hospitalier Est - Hôpital Neurologique

    Bron, 69677, France

  • Hop Guillaume Et Rene Laennec

    Saint-Herblain, 44800, France

  • Hopital B Roger Salengro

    Lille, 59037, France

  • Hospital Clinico Univ de Chile

    Santiago, Chile

  • Hospital General De Catalunya

    Sant Cugat del Vallès, Barcelona, 8195, Spain

  • Hospital Quiron de Madrid

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Dr. Peset

    Valencia, 46017, Spain

  • Hospital Universitario Reina Sofia

    Córdoba, 14004, Spain

  • Hospital Universitario la Fe

    Valencia, 46026, Spain

  • Hospital Victoria Eugenia

    Seville, 41009, Spain

  • Hospital Virgen del Rocío

    Seville, 41013, Spain

  • Hôpital Lariboisière

    Paris, 75010, France

  • Hôpital Robertsau

    Strasbourg, 67000, France

  • Hôpital de la Timone

    Marseille, 13385, France

  • IRCCS Ospedale San Raffaele

    Milan, Lombardy, 20132, Italy

  • Inha University Hospital

    Incheon, 22332, South Korea

  • Manchester Mental Health and Social Care Trust

    Manchester, M13 9WL, United Kingdom

  • NEURO-CARE Sp. z o.o. Sp. Komandytowa

    Katowice, 40-749, Poland

  • NZOZ Vitamed

    Bydgoszcz, 85-079, Poland

  • NZOZ WCA

    Wroc?aw, 53-659, Poland

  • Ospedale Cardinale Panico

    Tricase (LE), Apulia, 73039, Italy

  • Podlaskie Centrum Psychogeriatrii

    Bia?ystok, 15-756, Poland

  • Policlínica Guipuzcoa

    Donostia / San Sebastian, Guipuzcoa, 20014, Spain

  • ProNeuro Centrum Medyczne

    ?ory, 44-240, Poland

  • RE:Cognition Health

    London, W1G 8TA, United Kingdom

  • Rigshospitalet, Hukommelsesklinikken

    Koebenhavn Oe, 2100, Denmark

  • Scottish Brain Sciences

    Edinburgh, EH12 9DQ, United Kingdom

  • Senior Sp. Z O.O. Poradnia Psychogeriatryczna

    Sopot, 81-855, Poland

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • Surrey and Borders NHS Foundation Trust

    Chertsey, KT16 9AU, United Kingdom

  • Szpital Uniwersytecki w Krakowie

    Krakow, 30-688, Poland

  • TUM Klinikum rechts der Isar;Ambulanz für neurokognitive Erkrankungen

    München, 81675, Germany

  • Umberto I Policlinico di Roma-Università di Roma La Sapienza

    Rome, Lazio, 00185, Italy