Race to stop Alzheimer's before it starts in High-Risk families

NCT ID NCT06647498

Summary

This study is testing an investigational drug, remternetug, to see if it can prevent or slow the progression of Alzheimer's disease in people who carry a genetic mutation that causes the disease but do not yet have any symptoms. The trial will involve 280 participants who are 18 or older and are 11 to 25 years away from their predicted age of symptom onset. Researchers will use brain scans and other tests to measure if the drug successfully reduces the buildup of amyloid protein, a key marker of Alzheimer's, over two years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advocate Lutheran General Hospital

    RECRUITING

    Park Ridge, Illinois, 60068, United States

    Contact

  • Alzheimer's Research Australia

    NOT_YET_RECRUITING

    Melbourne, Victoria, 3010, Australia

    Contact

  • Azienda Ospedaliera Universitaria Careggi

    NOT_YET_RECRUITING

    Florence, 50134, Italy

    Contact

  • Brain Research Center

    NOT_YET_RECRUITING

    Amsterdam, 1081 GM, Netherlands

    Contact

  • Butler Hospital

    RECRUITING

    Providence, Rhode Island, 02096, United States

    Contact

  • CHU de Quebec - Hôpital de l' Enfant Jésus

    RECRUITING

    Québec, G1J 1Z4, Canada

    Contact

  • CHU de Rouen - Hôpital Charles Nicolle

    NOT_YET_RECRUITING

    Rouen, Seine Maritime, 76031, France

    Contact

  • CHU de Toulouse - Hôpital Purpan

    NOT_YET_RECRUITING

    Toulouse, Haute Garonne, 31059, France

    Contact

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30329, United States

    Contact

  • Groupe Hospitalier Pitie-Salpetriere

    NOT_YET_RECRUITING

    Paris, Paris, 69677, France

    Contact

  • Grupo de Neurociencias Sede de la Universidad de Antioquia

    RECRUITING

    Medellín, Colombia

    Contact

  • Hopital Neurologique Pierre Wertheimer

    NOT_YET_RECRUITING

    Bron, Rhone, 69677, France

    Contact

  • Hopital Roger Salengro - CHU Lille

    NOT_YET_RECRUITING

    Lille, Nord, 59037, France

    Contact

  • Hospital Clínic I Provincial de Barcelona

    NOT_YET_RECRUITING

    Barcelona, 8036, Spain

    Contact

  • IRCCS Centro San Giovanni di Dio Fatebenefratelli

    NOT_YET_RECRUITING

    Brescia, 25125, Italy

    Contact

  • Indiana University School of Medicine

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

  • Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez

    NOT_YET_RECRUITING

    Mexico City, Mexico City, 14269, Mexico

    Contact

  • Instituto de Investigaciones Neurologicas Raul Carrea, FLENI

    RECRUITING

    Ciudad Autonoma de Buenos Aire, C1428AQK, Argentina

    Contact

  • Kerwin Research and Memory Center

    RECRUITING

    Dallas, Texas, 75231, United States

    Contact

  • LMU-Campus Grosshadern

    NOT_YET_RECRUITING

    Munich, Bavaria, 81377, Germany

    Contact

  • McGill Center for Studies in Aging

    NOT_YET_RECRUITING

    Verdun, Quebec, H4H 1R3, Canada

    Contact

  • Neuroscience Research Australia

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact

  • New York University Medical Center

    RECRUITING

    New York, New York, 10016, United States

    Contact

  • New Zealand Brain Research Institute

    NOT_YET_RECRUITING

    Christchurch, 8011, New Zealand

    Contact

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact

  • The National Hospital for Neurology and Neurosurgery

    RECRUITING

    London, Greater London, WC1B 3BG, United Kingdom

    Contact

  • UBC Hospital

    RECRUITING

    Vancouver, British Columbia, V6T 2B5, Canada

    Contact

  • Universitaetsklinikum Tubingen

    NOT_YET_RECRUITING

    Tübingen, Baden-Wurttemberg, 72076, Germany

    Contact

  • University of Alabama in Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact

  • University of California San Diego Medical Center

    RECRUITING

    La Jolla, California, 92037, United States

    Contact

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

  • University of Puerto Rico, School of Medicine

    RECRUITING

    San Juan, 00936, Puerto Rico

    Contact

  • University of Washington

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact

  • Washington University in St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

  • Yale University School of Medicine

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact

Conditions

Explore the condition pages connected to this study.