Race against time: experimental drugs target inherited Alzheimer's before symptoms appear

NCT ID NCT01760005

Ongoing Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

Summary

This clinical trial is testing several different drugs to see if they can slow down or prevent cognitive decline in people who carry genetic mutations that cause inherited Alzheimer's disease. The study includes 490 participants who either have early symptoms or are still symptom-free but are expected to develop the disease based on family history. Researchers are using brain scans and cognitive tests to measure whether the treatments are working to control disease progression.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Advocate Lutheran General Hospital

Park Ridge, Illinois, 60068, United States
Alzheimer's Research Australia

Melbourne, Victoria, 3010, Australia
Azienda Ospedaliera Universitaria Careggi

Florence, 50134, Italy
Brain Research Center

Amsterdam, 1081 GM, Netherlands
Butler Hospital

Providence, Rhode Island, 02096, United States
CHU de Quebec - Hôpital de l' Enfant Jésus

Québec, G1J 1Z4, Canada
CHU de Rouen - Hôpital Charles Nicolle

Rouen, Seine Maritime, 76031, France
CHU de Toulouse - Hôpital Purpan

Toulouse, Haute Garonne, 31059, France
Emory University

Atlanta, Georgia, 30329, United States
Groupe Hospitalier Pitie-Salpetriere

Paris, Paris, 69677, France
Grupo de Neurociencias Sede de la Universidad de Antioquia

Medellín, Colombia
Hopital Neurologique Pierre Wertheimer

Bron, Rhone, 69677, France
Hopital Roger Salengro - CHU Lille

Lille, Nord, 59037, France
Hospital Clínic I Provincial de Barcelona

Barcelona, 8036, Spain
Hospital das Clínicas da Faculdade de Medicina da USP

São Paulo, 05403-000, Brazil
IRCCS Centro San Giovanni di Dio Fatebenefratelli

Brescia, 25125, Italy
Indiana University School of Medicine

Indianapolis, Indiana, 46202, United States
Instituto de Investigaciones Neurologicas Raul Carrea, FLENI

Ciudad Autonoma de Buenos Aire, C1428AQK, Argentina
Kerwin Medical Center

Dallas, Texas, 75231, United States
LMU-Campus Grosshadern

Munich, Bavaria, 81377, Germany
McGill Center for Studies in Aging

Verdun, Quebec, H4H 1R3, Canada
Neuroscience Research Australia

Randwick, New South Wales, 2031, Australia
Niigata University Medical & Dental Hospital

Niigata, Niigata, 951-8520, Japan
St Vincent's University Hospital

Dublin, DUBLIN 4, Ireland
Sunnybrook Health Sciences Centre

Toronto, Ontario, M4N 3M5, Canada
The McCuster Foundation of Alzheimer's Disease Research

Nedlands, Western Australia, 6009, Australia
The National Hospital for Neurology and Neurosurgery

London, Greater London, WC1B 3BG, United Kingdom
UBC Hospital

Vancouver, British Columbia, V6T 2B5, Canada
USC Keck School of Medicine

Los Angeles, California, 90033, United States
Universitaetsklinikum Tubingen

Tübingen, Baden-Wurttemberg, 72076, Germany
University of Alabama in Birmingham

Birmingham, Alabama, 35294, United States
University of California San Diego Medical Center

La Jolla, California, 92037, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States
University of Puerto Rico, School of Medicine

San Juan, 00936, Puerto Rico
University of Tokyo Hospital

Bunkyō City, Tokyo-To, 113-8655, Japan
University of Washington

Seattle, Washington, 98195, United States
Washington University in St. Louis

St Louis, Missouri, 63110, United States
Yale University School of Medicine

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

ALZHEIMERS DISEASE ALZHEIMERS DISEASE, FAMILIAL DEMENTIA