New Alzheimer's drug enters early safety testing

NCT ID NCT07234942

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 4 times

Summary

This early-stage study tests a new drug called RO7812653 in 50 people with early Alzheimer's disease. The main goal is to check if the drug is safe and how the body handles it. Participants receive a single dose injected into the spine and are closely monitored for side effects.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER'S DISEASE

Contacts and locations

Locations

Brain Research Center Amsterdam
RECRUITING

Amsterdam, North Holland, 1081 HV, Netherlands
Hospital General de Catalunya
RECRUITING

Sant Cugat del Vallès, Barcelona, 08190, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, 14004, Spain
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08025, Spain
Institute of Psychiatry, Psychology and Neuroscience;Department of Old Age Psychiatry
RECRUITING

London, Greater London, SE5 8AF, United Kingdom
Karolinska Universitetssjukhuset
RECRUITING

Solna, 171 76, Sweden
Montreal Neurological Institute Clinical Research Unit
RECRUITING

Montreal, Quebec, H3A 2B4, Canada
National Hospital For Neurology and Neurosurgery
RECRUITING

London, WC1N 3BG, United Kingdom
Queen Elizabeth Hospital
RECRUITING

Glasgow, Strathclyde, G21 3UW, United Kingdom
Sahlgrenska Universitetssjukhuset
RECRUITING

Mlndal, 43180, Sweden
Southampton General Hospital
RECRUITING

Southampton, Hampshire, SO16 6YD, United Kingdom
Toronto Western Hospital
RECRUITING

Toronto, Ontario, M5T 2S8, Canada

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