New hope for kidney transplant patients facing rejection

NCT ID NCT06744647

Recruiting now Disease control Sponsor: Alexion Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new drug called ALXN2030 in 45 adults who have had a kidney transplant and are experiencing antibody-mediated rejection (AMR). The goal is to see if the drug can help resolve signs of rejection seen on a kidney biopsy after one year of treatment. Participants will receive either ALXN2030 or a placebo, and their kidney function and safety will be monitored.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMR ANTIBODY-MEDIATED REJECTION BIOPSY-PROVEN HISTOLOGIC SCORES KIDNEY TRANSPLANTATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Research Site
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Birmingham, Alabama, 35249, United States
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Scottsdale, Arizona, 85259, United States
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Los Angeles, California, 90095, United States
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Orange, California, 92868, United States
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Tampa, Florida, 33606, United States
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Atlanta, Georgia, 30309, United States
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Kansas City, Kansas, 66160, United States
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Ann Arbor, Michigan, 48109, United States
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Detroit, Michigan, 48202, United States
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Livingston, New Jersey, 07039, United States
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WITHDRAWN

New York, New York, 10016, United States
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New York, New York, 10021, United States
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New York, New York, 10029, United States
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New York, New York, 10032, United States
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Durham, North Carolina, 27705, United States
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NOT_YET_RECRUITING

Cincinnati, Ohio, 45267, United States
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NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19140, United States
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WITHDRAWN

Charleston, South Carolina, 29425, United States
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Dallas, Texas, 75235, United States
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Houston, Texas, 77030, United States
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Richmond, Virginia, 23298, United States
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Seattle, Washington, 98195, United States
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Milwaukee, Wisconsin, 53226, United States
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Botucatu, 18618-687, Brazil
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Campinas, 13083, Brazil
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Porto Alegre, 90020-090, Brazil
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São Paulo, 04038-002, Brazil
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São Paulo, 05403-900, Brazil
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Calgary, Alberta, T2N 1N4, Canada
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Edmonton, Alberta, T6G 2R7, Canada
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Vancouver, British Columbia, V6Z 1Y6, Canada
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London, Ontario, N6A 5A5, Canada
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NOT_YET_RECRUITING

Toronto, Ontario, M5G 2N2, Canada
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WITHDRAWN

Montreal, Quebec, H4A 3J1, Canada
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Changsha, 430033, China
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Guangzhou, 510080, China
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Nanning, 530007, China
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Shanghai, 201114, China
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Wuhan, 430030, China
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Xi'an, 710061, China
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Seoul, 02841, South Korea
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Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Seoul, 3722, South Korea
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Barcelona, 08035, Spain
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Barcelona, 8003, Spain
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Zaragoza, 50009, Spain
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Kaohsiung City, 813, Taiwan
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Kaohsiung City, 833401, Taiwan
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Taichung, 40705, Taiwan
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WITHDRAWN

Taoyuan, 333, Taiwan
Research Site
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Birmingham, B15 2GW, United Kingdom
Research Site
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London, NW3 2QG, United Kingdom
Research Site
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London, W12 0HS, United Kingdom