Halted trial tests new shot at slowing devastating ALS

NCT ID NCT04494256

Summary

This study tested an experimental drug called BIIB105 in adults with ALS (amyotrophic lateral sclerosis). The drug was designed to lower levels of a protein linked to the disease and was given via spinal injection. The main goals were to check the drug's safety and see if it could slow the worsening of symptoms like muscle strength and breathing.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • A.O.U. Città della salute e della scienza di Torino

    Torino, Italy

  • ALS Clinic - Department of Neurology, Neuromuscular Division, Johns Hopkins University, School of Medicine

    Baltimore, Maryland, 21218, United States

  • Barrow Neurological Institute

    Phoenix, Arizona, 85013, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007-2113, United States

  • Houston Methodist Neurological Institute

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Montreal Neurological Institute-Hospital

    Montreal, Quebec, H3A 2B4, Canada

  • Orlando Health

    Orlando, Florida, 32806, United States

  • Stanford Neuromuscular Research Center

    Palo Alto, California, 94305, United States

  • The Emory Clinic

    Atlanta, Georgia, 30322, United States

  • UMC Utrecht

    Utrecht, 3584 CX, Netherlands

  • University of California San Diego Medical Center

    La Jolla, California, 92037, United States

  • University of Colorado Hospital - Neuroscience Center -Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah

    Salt Lake City, Utah, 84132, United States

  • Washington University, School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.