Painless muscle test could speed up ALS diagnosis

NCT ID NCT05104710

Recruiting now Diagnosis Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a quick, painless measurement of muscle activity using surface electrodes can help doctors diagnose ALS earlier and more accurately. Researchers will compare this test to current methods in 650 people with muscle symptoms. They will also track how the test changes over time in ALS patients to see if it matches disease progression.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a faster, more accurate way to diagnose ALS, helping patients get care sooner.
What could go wrong: This is an observational study, not a treatment trial. The test may not prove reliable enough for widespread use, and results may take years to confirm.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS

Contacts and locations

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
University of California Center for Clinical Research
ACTIVE_NOT_RECRUITING

Irvine, California, 92697, United States
University of Miami Miller School of Medicine
RECRUITING

Miami, Florida, 33136, United States
Washington University Medical Center
RECRUITING

St Louis, Missouri, 63110, United States

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