New drug aims to put the brakes on rare genetic kidney disease

NCT ID NCT07211685

Not yet recruiting Disease control Sponsor: Bayer Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an investigational drug called BAY 3401016 can slow the loss of kidney function in adults with Alport Syndrome, a rare genetic condition. Researchers will give the drug or a placebo to 60 participants aged 18-45 to see if it reduces protein in the urine, which is a sign of kidney damage. The main goal is to see if the drug can help protect the kidneys and delay the need for dialysis or transplant.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • All India Institute of Medical Sciences (AIIMS) - New Delhi

    New Delhi, 110 029, India

  • Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Necker-Enfants Malades - Service d'Hopital De Jour Néphrologie adulte

    Paris, 75015, France

  • Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - Nefrologia, Dialisi e Trapianto

    Bologna, 40138, Italy

  • Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia - Nefrologia

    Brescia, 25123, Italy

  • CHU bordeaux - Hopital Pellegrin - Service de Nephrologie-Transplantation-Dialyse-Aphereses

    Bordeaux, 33076, France

  • CHU de Brest - Hopital La Cavale Blanche - Service de Nephorologie-Hémodialyse-Transplantation

    Brest, 29200, France

  • CHU de Québec-Université Laval

    Québec, Quebec, G1R 2J6, Canada

  • CSK U.M. Lodz - Klin. Nefrologii, Hipertensjologii, Transplantologii i Chorób Wewnetrznych Samodz. Publiczny Zaklad OZ

    Lodz, 92-213, Poland

  • Cardio Renal Institute

    Chubbuck, Idaho, 83202, United States

  • Center for Advanced Pediatrics - Nephrology

    Atlanta, Georgia, 30329, United States

  • Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital de Rangueil - Nephrologie et transplantation d'organes

    Toulouse, 31400, France

  • Centro de Educacion Medica e Investigaciones Clinicas "Norberto Quirno" (CEMIC)

    Ciudad Autonoma de Buenos Aire, Buenos Aires, C1431FWO, Argentina

  • Centro de Rehabilitacion Cardiovascular | San Luis, Argentina

    San Luis, San Luis Province, D5700CGR, Argentina

  • Charité Mitte - Nephrologie und Internistische Intensivmedizin

    Berlin, 10117, Germany

  • Children's Hospital of Chongqing Medical University - Department of Nephrology

    Chongqing, Chongqing Municipality, 401122, China

  • Children's Hospital, Zhejiang University School of Medicine - Department of Nephrology

    Hangzhou, Zhejiang, 310052, China

  • Clinica de Nefrologia, Urologia y Enfermedades Cardiovasculares S.A.

    Santa Fe, S3000EPV, Argentina

  • Fakultní nemocnice Hradec Kralové - Nefrologická klinika

    Hradec Králové, 500 05, Czechia

  • Fundació Puigvert Enfermedades Renales Hereditarias. Servicio de Nefrología

    Barcelona, 8025, Spain

  • Hospital Británico

    Ciudad Autonoma de Buenos Aire, Buenos Aires, C1280AEB, Argentina

  • Hospital La Mancha Centro_Nephrology

    Alcázar de San Juan, Ciudad Real, 13600, Spain

  • Hospital Universitari Vall d´Hebron_ Nefrologia

    Barcelona, 08035, Spain

  • Hospital Universitario Fundacion Jimenez Diaz | Nephrology and Hypertension Department

    Madrid, 28040, Spain

  • Hospital Universitario Virgen del Rocio_Nephrology

    Seville, 41013, Spain

  • Hospital de Curry Cabral - Nephrology Department

    Lisbon, 1069-166, Portugal

  • Hospital de Torres Novas - Nephrology Department

    Torres Novas, 2350-399, Portugal

  • IRCCS Istituto Giannina Gaslini - Nefrologia e Trapianto Rene

    Genova, 16147, Italy

  • Japanese RedCross Aichi Medical Center Nagoya Daini Hospital

    Nagoya, Aichi-ken, 466-8650, Japan

  • K.G. Hospital

    Coimbatore, 641018, India

  • Kobe University Hospital

    Kobe, 650-0017, Japan

  • Lakeridge Health-Oshawa

    Oshawa, Ontario, L1G 2B9, Canada

  • Local Incorporated Administrative Agency Osaka City Hospital Organization Osaka City General Hospital

    Osaka, 534-0021, Japan

  • London Health Sciences Centre (LHSC) - University Hospital

    London, Ontario, N6A 5A5, Canada

  • Mavani Research Center

    Ahmedabad, Gujarat, 380052, India

  • McGill University Health Centre - Glen Site

    Montreal, Quebec, H4A 3J1, Canada

  • Nephrology Clinic at The Kirklin Clinic of UAB Hospital

    Birmingham, Alabama, 35233, United States

  • Ospedale Pediatrico Bambino Gesù - Nefrologia

    Roma, 00165, Italy

  • Peking University First Hospital - Department of Pediatrics

    Beijing, Beijing Municipality, 100000, China

  • Renal Disease Research Institute | Landry

    Dallas, Texas, 75246, United States

  • Royal Devon University Healthcare NHS Foundation Trust | Royal Devon and Exeter Hospital - Renal Unit

    Exeter, EX2 5DW, United Kingdom

  • Royal Free London NHS Foundation Trust | Royal Free Hospital - Centre for Nephrology

    London, NW3 2QG, United Kingdom

  • Saitama Prefectural Children's Medical Center

    Chuo-Ku, Saitama, 330-8777, Japan

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggido, 13620, South Korea

  • Seoul National University Hospital

    Seoul, Seoul Teugbyeolsi, 3080, South Korea

  • Sheffield Teaching Hospitals NHS Foundation Trust | Northern General Hospital - Sheffield Kidney Institute

    Sheffield, S5 7AU, United Kingdom

  • South Tyneside and Sunderland NHS Foundation Trust | Sunderland Royal Hospital - Renal Unit

    Sunderland, Tyne and Wear, SR4 7TP, United Kingdom

  • St. Joseph's Healthcare - Hamilton

    Hamilton, Ontario, L8N 4A6, Canada

  • The First Affiliated Hospital, Sun Yat-sen University - Department of Pediatrics

    Guangzhou, Guangdong, 510080, China

  • The Institute of Post Graduate Medical Education & Research (IPGMER) (SSKM Hospital)

    Kolkata, 700020, India

  • The Peggy and Harold Katz Family Drug Discovery Center - Nephrology

    Miami, Florida, 33136, United States

  • Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology - Pediatric Nephrology and Immunology

    Wuhan, Hubei, 430205, China

  • Tufts Medical Center | Nephrology Department

    Boston, Massachusetts, 02111, United States

  • ULS São João - Nephrology Department

    Porto, 4200-319, Portugal

  • Unidade Local de Saude de Gaia/Espinho E.P.E Nephrology Department

    Vila Nova de Gaia, 4434-502, Portugal

  • Universitaetsklinikum Erlangen - Medizinische Klinik 4, Nephrologie, Hypertensiologie

    Erlangen, 91054, Germany

  • Universitaetsklinikum Koeln - Klinik II fuer Innere Medizin - Nephrologie, Rheumatologie, Diabetologie, Innere Medizin

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Universitaetsmedizin Goettingen (UMG) - Klinik fuer Nephrologie und Rheumatologie

    Göttingen, Lower Saxony, 37075, Germany

  • Uniwersytecki Szpital Kliniczny w Poznaniu, Oddzial Kliniczny Nefrologii Transplantologii i Chorob Wewnetrznych

    Poznan, 60-355, Poland

  • Všeobecná fakultní nemocnice v Praze - Klinika nefrologie

    Prague, 128 08, Czechia

  • Wojskowy Instytut Medyczny Panstwowy Instytut Badawczy - Centrum Wsparcia Badan Klinicznych

    Warsaw, 04-141, Poland

Conditions

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