New drug aims to put the brakes on rare genetic kidney disease
NCT ID NCT07211685
Summary
This study is testing whether an investigational drug called BAY 3401016 can slow the loss of kidney function in adults with Alport Syndrome, a rare genetic condition. Researchers will give the drug or a placebo to 60 participants aged 18-45 to see if it reduces protein in the urine, which is a sign of kidney damage. The main goal is to see if the drug can help protect the kidneys and delay the need for dialysis or transplant.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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All India Institute of Medical Sciences (AIIMS) - New Delhi
New Delhi, 110 029, India
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Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Necker-Enfants Malades - Service d'Hopital De Jour Néphrologie adulte
Paris, 75015, France
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Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - Nefrologia, Dialisi e Trapianto
Bologna, 40138, Italy
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Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia - Nefrologia
Brescia, 25123, Italy
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CHU bordeaux - Hopital Pellegrin - Service de Nephrologie-Transplantation-Dialyse-Aphereses
Bordeaux, 33076, France
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CHU de Brest - Hopital La Cavale Blanche - Service de Nephorologie-Hémodialyse-Transplantation
Brest, 29200, France
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CHU de Québec-Université Laval
Québec, Quebec, G1R 2J6, Canada
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CSK U.M. Lodz - Klin. Nefrologii, Hipertensjologii, Transplantologii i Chorób Wewnetrznych Samodz. Publiczny Zaklad OZ
Lodz, 92-213, Poland
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Cardio Renal Institute
Chubbuck, Idaho, 83202, United States
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Center for Advanced Pediatrics - Nephrology
Atlanta, Georgia, 30329, United States
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Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital de Rangueil - Nephrologie et transplantation d'organes
Toulouse, 31400, France
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Centro de Educacion Medica e Investigaciones Clinicas "Norberto Quirno" (CEMIC)
Ciudad Autonoma de Buenos Aire, Buenos Aires, C1431FWO, Argentina
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Centro de Rehabilitacion Cardiovascular | San Luis, Argentina
San Luis, San Luis Province, D5700CGR, Argentina
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Charité Mitte - Nephrologie und Internistische Intensivmedizin
Berlin, 10117, Germany
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Children's Hospital of Chongqing Medical University - Department of Nephrology
Chongqing, Chongqing Municipality, 401122, China
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Children's Hospital, Zhejiang University School of Medicine - Department of Nephrology
Hangzhou, Zhejiang, 310052, China
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Clinica de Nefrologia, Urologia y Enfermedades Cardiovasculares S.A.
Santa Fe, S3000EPV, Argentina
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Fakultní nemocnice Hradec Kralové - Nefrologická klinika
Hradec Králové, 500 05, Czechia
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Fundació Puigvert Enfermedades Renales Hereditarias. Servicio de Nefrología
Barcelona, 8025, Spain
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Hospital Británico
Ciudad Autonoma de Buenos Aire, Buenos Aires, C1280AEB, Argentina
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Hospital La Mancha Centro_Nephrology
Alcázar de San Juan, Ciudad Real, 13600, Spain
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Hospital Universitari Vall d´Hebron_ Nefrologia
Barcelona, 08035, Spain
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Hospital Universitario Fundacion Jimenez Diaz | Nephrology and Hypertension Department
Madrid, 28040, Spain
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Hospital Universitario Virgen del Rocio_Nephrology
Seville, 41013, Spain
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Hospital de Curry Cabral - Nephrology Department
Lisbon, 1069-166, Portugal
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Hospital de Torres Novas - Nephrology Department
Torres Novas, 2350-399, Portugal
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IRCCS Istituto Giannina Gaslini - Nefrologia e Trapianto Rene
Genova, 16147, Italy
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Japanese RedCross Aichi Medical Center Nagoya Daini Hospital
Nagoya, Aichi-ken, 466-8650, Japan
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K.G. Hospital
Coimbatore, 641018, India
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Kobe University Hospital
Kobe, 650-0017, Japan
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Lakeridge Health-Oshawa
Oshawa, Ontario, L1G 2B9, Canada
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Local Incorporated Administrative Agency Osaka City Hospital Organization Osaka City General Hospital
Osaka, 534-0021, Japan
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London Health Sciences Centre (LHSC) - University Hospital
London, Ontario, N6A 5A5, Canada
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Mavani Research Center
Ahmedabad, Gujarat, 380052, India
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McGill University Health Centre - Glen Site
Montreal, Quebec, H4A 3J1, Canada
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Nephrology Clinic at The Kirklin Clinic of UAB Hospital
Birmingham, Alabama, 35233, United States
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Ospedale Pediatrico Bambino Gesù - Nefrologia
Roma, 00165, Italy
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Peking University First Hospital - Department of Pediatrics
Beijing, Beijing Municipality, 100000, China
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Renal Disease Research Institute | Landry
Dallas, Texas, 75246, United States
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Royal Devon University Healthcare NHS Foundation Trust | Royal Devon and Exeter Hospital - Renal Unit
Exeter, EX2 5DW, United Kingdom
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Royal Free London NHS Foundation Trust | Royal Free Hospital - Centre for Nephrology
London, NW3 2QG, United Kingdom
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Saitama Prefectural Children's Medical Center
Chuo-Ku, Saitama, 330-8777, Japan
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggido, 13620, South Korea
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Seoul National University Hospital
Seoul, Seoul Teugbyeolsi, 3080, South Korea
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Sheffield Teaching Hospitals NHS Foundation Trust | Northern General Hospital - Sheffield Kidney Institute
Sheffield, S5 7AU, United Kingdom
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South Tyneside and Sunderland NHS Foundation Trust | Sunderland Royal Hospital - Renal Unit
Sunderland, Tyne and Wear, SR4 7TP, United Kingdom
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St. Joseph's Healthcare - Hamilton
Hamilton, Ontario, L8N 4A6, Canada
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The First Affiliated Hospital, Sun Yat-sen University - Department of Pediatrics
Guangzhou, Guangdong, 510080, China
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The Institute of Post Graduate Medical Education & Research (IPGMER) (SSKM Hospital)
Kolkata, 700020, India
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The Peggy and Harold Katz Family Drug Discovery Center - Nephrology
Miami, Florida, 33136, United States
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Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology - Pediatric Nephrology and Immunology
Wuhan, Hubei, 430205, China
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Tufts Medical Center | Nephrology Department
Boston, Massachusetts, 02111, United States
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ULS São João - Nephrology Department
Porto, 4200-319, Portugal
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Unidade Local de Saude de Gaia/Espinho E.P.E Nephrology Department
Vila Nova de Gaia, 4434-502, Portugal
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Universitaetsklinikum Erlangen - Medizinische Klinik 4, Nephrologie, Hypertensiologie
Erlangen, 91054, Germany
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Universitaetsklinikum Koeln - Klinik II fuer Innere Medizin - Nephrologie, Rheumatologie, Diabetologie, Innere Medizin
Cologne, North Rhine-Westphalia, 50937, Germany
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Universitaetsmedizin Goettingen (UMG) - Klinik fuer Nephrologie und Rheumatologie
Göttingen, Lower Saxony, 37075, Germany
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Uniwersytecki Szpital Kliniczny w Poznaniu, Oddzial Kliniczny Nefrologii Transplantologii i Chorob Wewnetrznych
Poznan, 60-355, Poland
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Všeobecná fakultní nemocnice v Praze - Klinika nefrologie
Prague, 128 08, Czechia
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Wojskowy Instytut Medyczny Panstwowy Instytut Badawczy - Centrum Wsparcia Badan Klinicznych
Warsaw, 04-141, Poland
Conditions
Explore the condition pages connected to this study.