New drug targets Parkinson's protein in Early-Stage trial

NCT ID NCT07216066

First seen Nov 01, 2025 · Last updated May 02, 2026 · Updated 22 times

Summary

This study tests an experimental drug called ALN-SNCA in 46 people with early Parkinson's disease. The drug aims to lower a harmful protein (alpha-synuclein) in the fluid around the brain and spinal cord. The main goal is to check if the drug is safe and tolerable, and to see how it affects the body. This is a first-in-human trial, so it focuses on safety and dosing, not yet on curing the disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PARKINSONS DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Human Drug Research

    RECRUITING

    Leiden, South Holland, 2333 CL, Netherlands

  • Montreal Neurological Institute and Hospital

    RECRUITING

    Montreal, Quebec, H3A 2B4, Canada

Conditions

Explore the condition pages connected to this study.