New hope for PNH patients with stubborn anemia
NCT ID NCT07187401
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called ALN-CFB in people with paroxysmal nocturnal hemoglobinuria (PNH) who still have low red blood cells despite standard treatment. The goal is to see if adding ALN-CFB is safe and can improve anemia. About 24 participants will receive either the drug or a placebo, and researchers will monitor side effects and blood levels.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Kings College Hospital NHS Foundation Trust
RECRUITINGLondon, SE5 9RS, United Kingdom
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Samsung Medical Center
RECRUITINGSeoul, 6351, South Korea
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Seoul National University Hospital
RECRUITINGSeoul, 03080, South Korea
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Severance Hospital
RECRUITINGSeoul, 3722, South Korea
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St. James's University Hospital
RECRUITINGLeeds, West Yorkshire, LS97TF, United Kingdom
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St. Vincent Hospital - The Catholic University of Korea
RECRUITINGSuwon, Gyeonggi-do, 16247, South Korea
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The Catholic University of Korea, Seoul St. Mary's Hospital
RECRUITINGSeoul, 06591, South Korea
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Toronto General Hospital
RECRUITINGToronto, Ontario, M5G 2C4, Canada