New hope for PNH patients: experimental drug SLN12140 enters phase II trial

NCT ID NCT07387302

First seen Feb 04, 2026 · Last updated May 09, 2026 · Updated 8 times

Summary

This study tests whether the drug SLN12140 can control PNH, a rare blood disorder that destroys red blood cells. Ten adults who have not received prior complement inhibitor therapy will receive SLN12140 and be monitored for safety and effectiveness. The main goal is to see if the drug reduces a key blood marker (LDH) by at least 60% within 12 weeks.

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Contacts and locations

Study contacts

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Conditions

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