New shot aims to lower blood pressure for months

NCT ID NCT07553442

Recruiting now Disease control Sponsor: Alnylam Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study tests a single dose of an experimental drug called ALN-AGT01 in adults with mild to moderate high blood pressure who have already been treated with another drug, zilebesiran. The goal is to see if it safely helps control blood pressure by measuring changes in blood pressure and a related protein. About 93 participants will be randomly assigned to receive the drug or a placebo.

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Conditions

The condition(s) this trial relates to.

benign essential hypertension hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

Locations

Clinical Trial Site
RECRUITING

Lake Forest, California, 92630, United States
Clinical Trial Site
ACTIVE_NOT_RECRUITING

Tampa, Florida, 33613, United States
Clinical Trial Site
ACTIVE_NOT_RECRUITING

Savannah, Georgia, 31405, United States

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