New trial aims to boost leukemia transplant success with stronger prep regimen
NCT ID NCT03821610
First seen May 05, 2026 · Last updated May 05, 2026
Summary
This study compares two different chemotherapy combinations given before a stem cell transplant for adults aged 40-70 with acute lymphoblastic leukemia (ALL) in remission. The goal is to see if a stronger regimen (cyclophosphamide plus low-dose radiation) can prevent the cancer from returning better than the standard milder chemotherapy, without increasing transplant risks. Up to 242 participants will be randomly assigned to one of the two treatments and followed for at least 3 years.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ACUTE LYMPHOBLASTIC LEUKEMIA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Barts Health Nhs Trust
London, E11BB, United Kingdom
-
Cambridge University Hospitals Nhs Foundation Trust
Cambridge, CB20QQ, United Kingdom
-
Cardiff and Vale University Health Board
Cardiff, CF144XW, United Kingdom
-
Central Manchester University Hospitals Nhs Foundation Trust
Manchester, United Kingdom
-
Heart of England Nhs Foundation Trust
Birmingham, B95ST, United Kingdom
-
Imperial College Healthcare Nhs Trust
London, W21NY, United Kingdom
-
Kings College Hospital
London, SE5 9RS, United Kingdom
-
Leeds Teaching Hospitals Nhs Trust
Leeds, LS9 7TF, United Kingdom
-
NHS Greater Glasgow and Clyde
Glasgow, G12 0YN, United Kingdom
-
Nottingham University Hospitals Nhs Trust
Nottingham, NG72UH, United Kingdom
-
Oxford University Hospitals Nhs Foundation Trust
Oxford, OX3 9DU, United Kingdom
-
Plymouth Hospitals Nhs Trust
Plymouth, PL68DH, United Kingdom
-
Sheffield Teaching Hospitals Nhs Foundation Trust
Sheffield, S57AU, United Kingdom
-
The Christie Nhs Foundation Trust
Manchester, M204BX, United Kingdom
-
The Clatterbridge Cancer Centre Nhs Foundation Trust
Liverpool, CH634JY, United Kingdom
-
The Newcastle Upon Tyne Hospitals Nhs Foundation Trust
Newcastle, United Kingdom
-
The Royal Marsden Nhs Foundation Trust
London, SW3 6JJ, United Kingdom
-
University College London Hospitals Nhs Foundation Trust
London, NW12PG, United Kingdom
-
University Hospital Southampton Nhs Foundation Trust
Southampton, SO16 6YD, United Kingdom
-
University Hospitals Birmingham Nhs Foundation Trust
Birmingham, United Kingdom
-
University Hospitals Bristol Nhs Foundation Trust
Bristol, BS13NU, United Kingdom
-
University Hospitals of Leicester Nhs Trust
Leicester, LE15WW, United Kingdom
Conditions
Explore the condition pages connected to this study.