Alcohol injection to zap high blood pressure? new trial tests One-Time fix

NCT ID NCT07083765

Terminated Disease control Sponsor: Ablative Solutions, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests a procedure called renal denervation, where a small amount of alcohol is injected around the kidney nerves to calm overactive signals that raise blood pressure. 142 people with uncontrolled hypertension will either get the real procedure or a sham (fake) procedure, and stop their blood pressure pills for 13 weeks. The goal is to see if this one-time treatment can safely lower blood pressure without needing daily medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dehydrated alcohol injection
What this could lead to: If it works, this could offer a one-time procedure to control high blood pressure without needing daily pills.
What could go wrong: The trial is currently suspended, and it's a small, early-phase study. The procedure involves risks like kidney or blood vessel damage, and it may not lower blood pressure enough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

essential hypertension essential hypertension, genetic hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION HYPERTENSION,ESSENTIAL

Contacts and locations

Locations

Tennova Turkey Creek Medical Center

Knoxville, Tennessee, 37934, United States

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