Gene study reveals why some people react differently to alcohol

NCT ID NCT03294460

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 30 times

Summary

This study looks at how a specific gene (CHRNA5) might influence how people experience alcohol and how their brains respond to alcohol-related cues. Healthy adults aged 21-60, both smokers and non-smokers, will receive alcohol through an IV or drink it while researchers monitor their brain activity with MRI and track their drinking behavior. The goal is to understand why some people are more at risk for alcohol use disorder.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.