New blood test aims to catch lung transplant problems early

NCT ID NCT05050955

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a blood test called AlloSure Lung in 550 lung transplant patients. The test looks for DNA from the donor lung in the patient's blood, which could signal rejection or infection. Researchers want to see how accurate the test is compared to standard monitoring. The study is observational, meaning it only watches and measures—it does not test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AlloSure Lung (donor-derived cell-free DNA blood test)

What this could lead to

If successful, this blood test could help doctors spot lung transplant rejection or infection earlier, potentially improving patient outcomes.

What could go wrong

This is an observational registry, not a treatment trial. The test may not prove accurate enough to change standard care, and results may not apply to all transplant patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Rejection, Psychology transplant rejection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AdventHealth Orlando

    Orlando, Florida, 32804, United States

  • Brigham and Womens Hospital

    Boston, Massachusetts, 02115, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Columbia University Medical Center

    New York, New York, 10027, United States

  • Inova

    Falls Church, Virginia, 22042, United States

  • Loyola University Medical School

    Maywood, Illinois, 60153, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • St. Joseph's Hospital & Medical Center

    Phoenix, Arizona, 85013, United States

  • Temple University

    Philadelphia, Pennsylvania, 19140, United States

  • Toronto General Hospital

    Toronto, Ontario, M5G 2C4, Canada

  • UT Health/ Memorial Hermann Hospital

    Houston, Texas, 77030, United States

  • University of Alabama (UAB)

    Birmingham, Alabama, 35233, United States

  • University of CO Anschutz Medical Campus

    Aurora, Colorado, 80045, United States

  • University of California (UCSF) School of Medicine

    San Francisco, California, 94143, United States

  • University of Louisville Health

    Louisville, Kentucky, 40202, United States

  • University of Mayland

    Baltimore, Maryland, 21201, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Wisconsin Madison

    Madison, Wisconsin, 53792, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Washington University-Barnes Jewish Hospital

    St Louis, Missouri, 63110, United States