New blood test aims to catch lung transplant problems early
NCT ID NCT05050955
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a blood test called AlloSure Lung in 550 lung transplant patients. The test looks for DNA from the donor lung in the patient's blood, which could signal rejection or infection. Researchers want to see how accurate the test is compared to standard monitoring. The study is observational, meaning it only watches and measures—it does not test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AlloSure Lung (donor-derived cell-free DNA blood test)
- What this could lead to
- If successful, this blood test could help doctors spot lung transplant rejection or infection earlier, potentially improving patient outcomes.
- What could go wrong
- This is an observational registry, not a treatment trial. The test may not prove accurate enough to change standard care, and results may not apply to all transplant patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LUNG TRANSPLANT FAILURE AND REJECTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AdventHealth Orlando
Orlando, Florida, 32804, United States
-
Brigham and Womens Hospital
Boston, Massachusetts, 02115, United States
-
Cedars Sinai Medical Center
Los Angeles, California, 90048, United States
-
Columbia University Medical Center
New York, New York, 10027, United States
-
Inova
Falls Church, Virginia, 22042, United States
-
Loyola University Medical School
Maywood, Illinois, 60153, United States
-
Montefiore Medical Center
The Bronx, New York, 10467, United States
-
NYU Langone Health
New York, New York, 10016, United States
-
Ohio State University
Columbus, Ohio, 43210, United States
-
St. Joseph's Hospital & Medical Center
Phoenix, Arizona, 85013, United States
-
Temple University
Philadelphia, Pennsylvania, 19140, United States
-
Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
-
UT Health/ Memorial Hermann Hospital
Houston, Texas, 77030, United States
-
University of Alabama (UAB)
Birmingham, Alabama, 35233, United States
-
University of CO Anschutz Medical Campus
Aurora, Colorado, 80045, United States
-
University of California (UCSF) School of Medicine
San Francisco, California, 94143, United States
-
University of Louisville Health
Louisville, Kentucky, 40202, United States
-
University of Mayland
Baltimore, Maryland, 21201, United States
-
University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
-
University of Wisconsin Madison
Madison, Wisconsin, 53792, United States
-
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
-
Washington University-Barnes Jewish Hospital
St Louis, Missouri, 63110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A smartphone tool may help cystic fibrosis patients survive the lung transplant waitlist
- Lung transplant patients followed for years to uncover Long-Term health secrets
- New drug may protect kidneys in lung transplant patients
- Blood test may let lung transplant patients ditch antiviral drugs sooner
- Massive lung transplant study seeks 2,600 patients to unlock better care
- Could hepatitis c positive lungs save lives? pilot study explores new transplant option