New hope for stubborn thyroid cancer: experimental drug aims to slow tumor growth
NCT ID NCT06860971
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the experimental drug AL2846 can slow cancer growth in people with advanced thyroid cancer that no longer responds to radioiodine or previous targeted therapy. About 144 participants will receive either AL2846 or a placebo. The main goal is to see how long people live without their cancer getting worse.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED OR METASTATIC RADIOIODINE-REFRACTORY DIFFERENTIATED THYROID CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Affiliated Hospital of Guilin Medical University
NOT_YET_RECRUITINGGui'lin, Guangxi, 541001, China
-
Affiliated Tumor Hospital of Xinjiang Medical University
NOT_YET_RECRUITINGÜrümqi, Xinjiang, 841100, China
-
CangZhou Center Hospital
NOT_YET_RECRUITINGCangzhou, Hebei, 61012, China
-
China-Japan Union Hospital of Jilin University
NOT_YET_RECRUITINGChangchun, Jilin, 130000, China
-
Fujian Medical University Union Hospital
NOT_YET_RECRUITINGFuzhou, Fujian, 350001, China
-
Gansu Provincial Cancer Hospital
NOT_YET_RECRUITINGLanzhou, Gansu, 730050, China
-
Harbin Medical University cancer hospital
NOT_YET_RECRUITINGHarbin, Heilongjiang, 150081, China
-
Henan Cancer Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450000, China
-
Hunan Cancer Hospital
NOT_YET_RECRUITINGChangsha, Hunan, 410000, China
-
JIANGXI cancer hospital
NOT_YET_RECRUITINGNanchang, Jiangxi, 330029, China
-
JILIN cancer hospital
NOT_YET_RECRUITINGChangchun, Jilin, 130000, China
-
Liaoning Cancer Hospital
NOT_YET_RECRUITINGShengyang, Liaoning, 110000, China
-
Nanjing First Hospital
NOT_YET_RECRUITINGNanjing, Jiangsu, 210006, China
-
Shaanxi Provincial People'S Hospital
NOT_YET_RECRUITINGXi'an, Shaanxi, 710068, China
-
Shandong Cancer Hospital
NOT_YET_RECRUITINGJinan, Shandong, 250117, China
-
Shanghai Jiaotong University School of Medicine, Tongji Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200120, China
-
Shanghai Sixth People's Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200030, China
-
Sun Yat-sen University Cancer Center
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510060, China
-
The Affiliated Hospital of XuZhou Medical University
NOT_YET_RECRUITINGXuzhou, Jiangsu, 21002, China
-
The First Affiliated Hospital of Hainan Medical University
NOT_YET_RECRUITINGHainan, Haikou, 570102, China
-
The First Affiliated Hospital of Xi'an Jiao Tong University
NOT_YET_RECRUITINGXi'an, Shaani, 710000, China
-
The Second Affiliated Hospital Of GXUST
NOT_YET_RECRUITINGLiuzhou, Guangxi, 545006, China
-
The Second Affiliated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, Jiangxi, 330006, China
-
The Second Hospital Of Anhui Medical University
NOT_YET_RECRUITINGHefei, Anhui, 230601, China
-
The Second Hospital of Shandong University
NOT_YET_RECRUITINGJinan, Shandong, 250033, China
-
The Southwest Hospital of Amu
NOT_YET_RECRUITINGChongqing, Chongqing Municipality, 400038, China
-
Tianjin Cancer Hospital Airport Hospital
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, 300070, China
-
Tianjin Medical University Cancer Institute&Hospital
RECRUITINGTianjin, Tianjin Municipality, 300202, China
-
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITINGWuhan, Hubei, 430000, China
-
Weifang people's Hospital
NOT_YET_RECRUITINGWeifang, Shandong, 261000, China
-
West China Hospital of Si chuan University
NOT_YET_RECRUITINGChengdu, Sichuan, 610000, China
-
Xijing Hospital
NOT_YET_RECRUITINGXi'an, Shaanxi, 710032, China
-
Yunnan Cancer Hospital
NOT_YET_RECRUITINGKunming, Yunnan, 650118, China
-
Zhejiang Cancer Hospital
NOT_YET_RECRUITINGHangzhou, Zhejiang, 310005, China
-
cancer hospital Chinese academy of medical sciences
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100021, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Genetic test may spare patients from unnecessary thyroid surgery
- Can a new oral drug outsmart Radioiodine-Resistant thyroid cancer?
- Can an immune booster make radioiodine more effective against thyroid cancer?
- Hidden thyroid cancers may be more common in Graves' disease than thought
- Can math make thyroid hormone therapy more precise?
- Can AI help surgeons see thyroid cancer more clearly?