New trial aims to boost survival in rare blood disease with stem cell transplant
NCT ID NCT06022939
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether adding a stem cell transplant to standard chemotherapy helps people with newly diagnosed AL amyloidosis. About 338 participants will receive either chemo alone or chemo followed by a stem cell transplant. The goal is to see which approach better delays organ damage and improves survival.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Daratumumab, cyclophosphamide, bortezomib, dexamethasone, melphalan, and autologous stem cell transplant
- What this could lead to
- If successful, this could show that adding a stem cell transplant to standard chemo helps people with AL amyloidosis live longer without major organ damage.
- What could go wrong
- This is a large phase 3 trial, but stem cell transplants carry serious risks like infection and organ damage. The added benefit over chemo alone is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 338 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2024
- Expected to finish
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Oct 2030
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * STEP 1: Participants must have systemic AL amyloidosis which is biopsy proven and includes histologically-confirmed by positive Congo red stain with green birefringence on polarized light microscopy, OR characteristic appearance by electron microscopy AND confirmatory AL amyloid typing (mass spectrometry-based proteomic analysis or immunofluorescence). If there is question regarding diagnosis, consult study chairs prior to registration * STEP 1: Participants must have measurable disease within 28 days prior to treatment if initiated prior to registration or within 28 days of registration as defined by at least one of the following: * Positive monoclonal serum immunofixation electrophoresis * Positive monoclonal urine immunofixation electrophoresis * Monoclonal plasma cells in bone marrow In addition, participants must also have a difference between the involved and uninvolved free light chain (dFLC) \>= 2 mg/dL * STEP 1: Participants may receive up to one cycle (or 28 days) of therapy prior to enrollment. If a patient receives \>= 75% of 1 cycle of protocol identical Dara-VCD, this will be considered 1 cycle of protocol induction. Any patient who receives less than 75% of 1 cycle of Dara-VCD or non-protocol therapy will still be eligible but will be treated per protocol. If protocol identical therapy is initiated prior to enrollment, this treatment is not continued but rather treatment is dictated per protocol * STEP 1: Participants may be receiving chronic corticosteroids if they are being given for disorders other than AL amyloidosis or myeloma * STEP 1: Participant must be \>= 18 years old * STEP 1: Participant must have Eastern Cooperative Oncology Group (ECOG) performance score (PS) of 0, 1, or 2 (PS = 3 may be allowed if secondary to neuropathy) * STEP 1: Participant must have a complete medical history and physical exam within 28 DAYS prior to registration * STEP 1: Participants must be willing to undergo high dose chemotherapy and autologous stem cell transplantation if they are randomized to the arm receiving high dose chemotherapy and autologous stem cell transplantation * STEP 1: Participants must be eligible to receive high dose chemotherapy with melphalan at a dose of 200 mg/m\^2 or 140 mg/m\^2 (200 mg/m\^2 is highly encouraged but not mandated). Transplant eligibility criteria are included in the general eligibility criteria listed below: * Participant must have a supine systolic blood pressure (BP) \>= 90 mmHg (at registration step-1, this may by supported by midodrine * Participant must have non-severe cardiac AL (meeting all the below criteria) as defined by: * N-terminal proB-type natriuretic peptide (NT proBNP) \< 5000 (if no NTproBNP, brain natriuretic peptide \[BNP\] must be available and \< 400) * Troponin T (TnT) \< 0.06. If not available, one of the following two criteria must be met: * High sensitivity troponin (hsTnT) T \< 75 or troponin I \< 0.1ng/dL * New York Heart Association (NYHA) I or II * Cardiac ejection fraction (EF) \>= 40% * STEP 1: Hemoglobin \>= 8.0 g/dL (\> 5 mmol/L); red blood cell transfusion allowed up to 7 day prior to registration (within 28 days prior to registration) (NOTE: Growth factor support granulocyte colony-stimulating factor \[G-CSF\] is permitted per institutional guidelines) * STEP 1: Leukocytes \>= 2 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 1: Absolute neutrophil count \>= 1.0 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 1: Platelets \>= 50 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 1: Total bilirubin =\< 1.5 times the institutional upper limit of normal (ULN) unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin =\< 5 x institutional ULN (within 28 days prior to registration) * STEP 1: Direct bilirubin =\< 2.0 mg/dL (within 28 days prior to registration) * STEP 1: Aspartate aminotransferase (AST)/ alanine aminotransferase (ALT) =\< 3x upper limit of normal (ULN) (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 1: Alkaline phosphatase =\< 750 U/L (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 1: Participants must have a serum creatinine =\< the institutional (I)ULN OR measured OR calculated creatinine clearance \>= 30 mL/min using the following Cockcroft-Gault formula. This specimen must have been drawn and processed within 28 days prior to registration * STEP 1: If peripheral neuropathy is present at diagnosis, participants must be grade 2 (moderate symptoms; limiting instrumental activity of daily living \[ADL\]) or less * STEP 1: Participants must have adequate cardiac function. Participants with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, must have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, participants must be class 2 or better * STEP 1: Participants must not be seropositive for hepatitis B (defined by a positive test for hepatitis B surface antigen \[HBsAg\]). Subjects with resolved infection (i.e., subjects who are HBsAg negative but positive for antibodies to hepatitis B core antigen \[anti-HBc\] and/or antibodies to hepatitis B surface antigen \[anti-HBs\]) must be screened using real-time polymerase chain reaction (PCR) measurement of hepatitis B virus (HBV) deoxyribonucleic acid (DNA) levels. Those who are PCR positive will be excluded. EXCEPTION: Subjects with serologic findings suggestive of HBV vaccination (anti-HBs positivity as the only serologic marker) AND a known history of prior HBV vaccination, do not need to be tested for HBV DNA by PCR * STEP 1: Participants with a history of hepatitis C virus (HCV) infection must have been treated and cured. Participants currently being treated for HCV infection must have undetectable HCV viral load test on the most recent test results obtained within 6 months prior to registration, if indicated * STEP 1: Participants must not have concurrent multiple myeloma as defined by the presence of lytic bone disease, plasmacytomas, \>= 60% plasma cells in the bone marrow, or hypercalcemia. Participants will not be excluded solely based on the presence of plasma cells \> 10% in the bone marrow unless the plasma cell percentage exceeds \>60% * STEP 1: Participants must not have known allergies to any of the study drugs * STEP 1: Participants must not have had a major surgery within 14 days prior to registration and be fully recovered from surgery completed within 14 days prior to registration * STEP 1: Participants must not have a known chronic obstructive pulmonary disease with a forced expiratory volume in 1 second (FEV1) \< 50% of predicted normal * STEP 1: Participants with known human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load test on the most recent test results obtained within 6 months prior to registration * STEP 1: Participants must not have either moderate or severe persistent asthma within the past 2 years), or currently have uncontrolled asthma of any classification. (Note that subjects who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed in the study) * STEP 1: Participants must not have uncontrolled diabetes within 28 days prior to registration * STEP 1: Participants must not have uncontrolled blood pressure and hypertension within 14 days prior to registration. Participants must have a supine systolic BP of \>= 90 mmHg * STEP 1: Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen * STEP 1: Participants must not have received vaccination with live attenuated vaccines within 28 days prior to Registration to Step 1 * STEP 1: Participants must not have uncontrolled infection at the discretion of the enrolling physician and to be discussed with the study chair if the participant is on active anti-infectious therapy. Any patient on active anti-microbial therapy for chronic infectious issues should be discussed with the study chair prior to enrollment * STEP 1: Participants must not be pregnant or nursing (nursing includes breast milk fed to an infant by any means, including from the breast, milk expressed by hand, or pumped). Individuals who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion, and vasectomy with testing showing no sperm in the semen * STEP 1: Participants must be offered the opportunity to participate in specimen banking. With participant consent, specimens must be collected and submitted via the Southwestern Oncology group (SWOG) Specimen Tracking System * STEP 1: Participants must agree to have blood, bone marrow core biopsy and aspirate, and fat pad biopsy specimens submitted for minimal residual disease assessment and future exploratory studies * STEP 1: Participants who can complete PRO, QOL, PRO-CTCAE questionnaires, etc. forms in English, Spanish and French must participate in the patient-reported outcomes and quality of life * STEP 2: Participants must have met all eligibility criteria for Step-1 registration * STEP 2: Participants must have achieved at least a partial response * STEP 2: Participants must continue receiving at least one of study drugs (bortezomib, cyclophosphamide, or daratumumab and hyaluronidase-fihj) if another study drug (daratumumab and hyaluronidase-fihj, cyclophosphamide, or bortezomib) has been discontinued due to adverse events. Note: daratumumab and hyaluronidase-fihj cannot be permanently discontinued * STEP 2: Participants must have completed induction therapy * STEP 2: Participants must be registered to Step 2 within 42 days of cycle 3, day 28 of induction therapy * STEP 2: Participants must plan to initiate their assigned consolidation therapy within 8 weeks after randomization * STEP 2: Participants must not have experienced a MOD-PFS event * STEP 2: Participants must have ECOG performance score (PS) of 0, 1, or 2 (PS = 3 may be allowed if secondary to neuropathy) * STEP 2: Participant must have a complete medical history and physical exam within 28 days prior to registration * STEP 2: Participants must be willing to undergo high dose chemotherapy and autologous stem cell transplantation if they are randomized to the arm receiving high dose chemotherapy and autologous stem cell transplantation * STEP 2: Participants randomized to Arm 2 must be willing and able to return to a participating treatment center for their assigned treatment after transplant. Note that participants need not to have a direct relationship with the transplant center in order to register * STEP 2: Participants must be eligible to receive high dose chemotherapy with melphalan at a dose of 200 mg/m\^2 or 140 mg/m\^2 (200 mg/m\^2 is highly encouraged but not mandated). Transplant eligibility criteria are included in the general eligibility criteria listed below: * Patient must have a supine systolic BP \>= 90 mmHg (at registration step-1, this may not by supported by midodrine) * Patient must have non-severe cardiac AL as defined by: * NT proBNP \<5000 (if no NTproBNP, BNP must be available and \< 400 pg/mL) (within 14 days prior to registration step-2) * TnT \< 0.06. If not available, one of the following two criteria must be met (within 14 days prior to registration step-2) * hsTnT \<75 or troponin I \< 0.1ng/dL * NYHA I or II (within 14 days prior to registration step-2) * Cardiac EF \>= 40% (within 14 days prior to registration step-2) * STEP 2: Hemoglobin \> 8.0 g/dL (\> 5 mmol/L); red blood cell transfusion allowed up to 7 days prior to registration (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 2: Leukocytes \>= 2 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 2: Absolute neutrophil count \>= 1.0 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 2: Platelets \>= 50 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 2: Total bilirubin =\< 1.5 times the institutional ULN unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin =\< 5 x institutional ULN (within 28 days prior to registration) * STEP 2: Direct bilirubin =\< 2.0 mg/dL (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 2: AST/ALT =\< 3x upper limit of normal (ULN) (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 2: Alkaline phosphatase =\< 750 U/L (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 2: Participants must have a serum creatinine =\< the IULN OR calculated creatinine clearance ≥ 30 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to registration * STEP 2: Participants must not have uncontrolled infection at the discretion of the enrolling physician and to be discussed with the study chair if the participant is on active anti-infectious therapy. Any patient on active anti-microbial therapy for chronic infectious issues should be discussed with the study chair prior to enrollment * STEP 2: Participants randomized to the ASCT arm must be able to have at least 2.0 x 10\^6 CD34 cells/kg collected * STEP 2: Participants who can complete PRO, QOL, PRO-CTCAE questionnaires, etc. forms in English, Spanish and French must participate in the patient-reported outcomes and quality of life * STEP 3: Participants must have met all eligibility criteria for Step-1 and Step-2 registration * STEP 3: Participants must not have had daratumumab and hyaluronidase-fihj permanently discontinued during induction or consolidation * STEP 3: Participants must have completed induction and consolidation therapy * STEP 3: Participants must be registered to Step 3 within the following time frames: * If randomized to Arm 1 Dara-VCD consolidation: within 28 days of completion of 3 cycles of consolidation therapy * If randomized to Arm 2 high dose chemotherapy and autologous stem cell transplantation: within 180 days following initiation of stem cell transplantation * STEP 3: Participants must not have experienced a MOD-PFS event * STEP 3: Participants must have ECOG performance score (PS) of 0, 1, or 2 (PS = 3 is allowed if secondary to neuropathy) * STEP 3: Participants must have a complete medical history and physical exam within 28 DAYS prior to registration * STEP 3: Hemoglobin \> 8.0 g/dL (\> 5 mmol/L); red blood cell transfusion allowed up to 7 days prior to registration (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 3: Leukocytes \>= 2 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 3: Absolute neutrophil count \>= 1.0 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 3: Platelets \>= 50 x 10\^3/uL (within 28 days prior to registration) (NOTE: Growth factor support \[G-CSF\] is permitted per institutional guidelines) * STEP 3: Total bilirubin =\< 1.5 times the institutional upper limit of normal (ULN) unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin =\< 5 x institutional ULN (within 28 days prior to registration) * STEP 3: Direct bilirubin =\< 2.0 mg/dL (within 28 days prior to registration) * STEP 3: AST/ALT =\< 3x upper limit of normal (ULN) (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 3: Alkaline phosphatase =\< 750 U/L (except if secondary to hepatic involvement) (within 28 days prior to registration) * STEP 3: Participants must not have uncontrolled infection at the discretion of the enrolling physician and to be discussed with the study chair if the participant is on active anti-infectious therapy. Any patient on active anti-microbial therapy for chronic infectious issues should be discussed with the study chair prior to enrollment * Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines. For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
116 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
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Abbott-Northwestern Hospital
RECRUITINGMinneapolis, Minnesota, 55407, United States
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Allegiance Health
RECRUITINGJackson, Michigan, 49201, United States
Contact Email: •••••@•••••
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Banner University Medical Center - Tucson
RECRUITINGTucson, Arizona, 85719, United States
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Baptist Memorial Hospital and Cancer Center-Collierville
RECRUITINGCollierville, Tennessee, 38017, United States
Contact Email: •••••@•••••
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Baptist Memorial Hospital and Cancer Center-Desoto
RECRUITINGSouthhaven, Mississippi, 38671, United States
Contact Email: •••••@•••••
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Baptist Memorial Hospital and Cancer Center-Memphis
RECRUITINGMemphis, Tennessee, 38120, United States
Contact Email: •••••@•••••
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Baptist Memorial Hospital and Cancer Center-Oxford
RECRUITINGOxford, Mississippi, 38655, United States
Contact Email: •••••@•••••
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Boston Medical Center
RECRUITINGBoston, Massachusetts, 02118, United States
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CTCA at Western Regional Medical Center
RECRUITINGGoodyear, Arizona, 85338, United States
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Carle Cancer Center
RECRUITINGUrbana, Illinois, 61801, United States
Contact Email: •••••@•••••
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Carle Physician Group-Effingham
RECRUITINGEffingham, Illinois, 62401, United States
Contact Email: •••••@•••••
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Carle Physician Group-Mattoon/Charleston
RECRUITINGMattoon, Illinois, 61938, United States
Contact Email: •••••@•••••
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Carle at The Riverfront
RECRUITINGDanville, Illinois, 61832, United States
Contact Email: •••••@•••••
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Case Western Reserve University
RECRUITINGCleveland, Ohio, 44106, United States
Contact Email: •••••@•••••
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City of Hope Comprehensive Cancer Center
RECRUITINGDuarte, California, 91010, United States
Contact Email: •••••@•••••
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City of Hope at Irvine Lennar
RECRUITINGIrvine, California, 92618, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Emory University Hospital Midtown
RECRUITINGAtlanta, Georgia, 30308, United States
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Emory University Hospital/Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
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Fairview Southdale Hospital
RECRUITINGEdina, Minnesota, 55435, United States
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Geisinger Medical Center
RECRUITINGDanville, Pennsylvania, 17822, United States
Contact Email: •••••@•••••
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Geisinger Wyoming Valley/Henry Cancer Center
RECRUITINGWilkes-Barre, Pennsylvania, 18711, United States
Contact Email: •••••@•••••
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Gundersen Lutheran Medical Center
RECRUITINGLa Crosse, Wisconsin, 54601, United States
Contact Email: •••••@•••••
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Henry Ford Cancer Institute-Downriver
RECRUITINGBrownstown, Michigan, 48183, United States
Contact Email: •••••@•••••
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Henry Ford Hospital
RECRUITINGDetroit, Michigan, 48202, United States
Contact Email: •••••@•••••
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Henry Ford Macomb Hospital-Clinton Township
RECRUITINGClinton Township, Michigan, 48038, United States
Contact Email: •••••@•••••
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Henry Ford Medical Center-Columbus
RECRUITINGNovi, Michigan, 48377, United States
Contact Email: •••••@•••••
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Henry Ford Medical Center-Fairlane
RECRUITINGDearborn, Michigan, 48126, United States
Contact Email: •••••@•••••
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Henry Ford West Bloomfield Hospital
RECRUITINGWest Bloomfield, Michigan, 48322, United States
Contact Email: •••••@•••••
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Henry Ford Wyandotte Hospital
RECRUITINGWyandotte, Michigan, 48192, United States
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Houston Methodist Cypress Hospital
RECRUITINGCypress, Texas, 77429, United States
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Houston Methodist Hospital
RECRUITINGHouston, Texas, 77030, United States
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Houston Methodist Saint John Hospital
RECRUITINGNassau Bay, Texas, 77058, United States
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Houston Methodist San Jacinto Hospital
RECRUITINGBaytown, Texas, 77521, United States
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Houston Methodist Sugar Land Hospital
RECRUITINGSugar Land, Texas, 77479, United States
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Houston Methodist The Woodlands Hospital
RECRUITINGThe Woodlands, Texas, 77385, United States
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Houston Methodist West Hospital
RECRUITINGHouston, Texas, 77094, United States
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Iowa Methodist Medical Center
RECRUITINGDes Moines, Iowa, 50309, United States
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Karmanos Cancer Institute at McLaren Greater Lansing
RECRUITINGLansing, Michigan, 48910, United States
Contact Email: •••••@•••••
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Loyola University Medical Center
RECRUITINGMaywood, Illinois, 60153, United States
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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MedStar Georgetown University Hospital
RECRUITINGWashington D.C., District of Columbia, 20007, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Bergen
RECRUITINGMontvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Memorial Sloan Kettering Commack
RECRUITINGCommack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
RECRUITINGMiddletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Westchester
RECRUITINGHarrison, New York, 10604, United States
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Mercy Hospital
RECRUITINGCoon Rapids, Minnesota, 55433, United States
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Methodist Willowbrook Hospital
RECRUITINGHouston, Texas, 77070, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
RECRUITINGNew York, New York, 10032, United States
Contact Email: •••••@•••••
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Nebraska Medicine-Bellevue
RECRUITINGBellevue, Nebraska, 68123, United States
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Nebraska Medicine-Village Pointe
RECRUITINGOmaha, Nebraska, 68118, United States
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Novant Health Cancer Institute - Huntersville
RECRUITINGHuntersville, North Carolina, 28078, United States
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Novant Health Cancer Institute - Mooresville
RECRUITINGMooresville, North Carolina, 28117, United States
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Novant Health Forsyth Medical Center
RECRUITINGWinston-Salem, North Carolina, 27103, United States
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Novant Health Presbyterian Medical Center
RECRUITINGCharlotte, North Carolina, 28204, United States
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Oregon Health and Science University
ACTIVE_NOT_RECRUITINGPortland, Oregon, 97239, United States
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Park Nicollet Clinic - Saint Louis Park
RECRUITINGSaint Louis Park, Minnesota, 55416, United States
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Providence Newberg Medical Center
RECRUITINGNewberg, Oregon, 97132, United States
Contact Email: •••••@•••••
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Providence Portland Medical Center
RECRUITINGPortland, Oregon, 97213, United States
Contact Email: •••••@•••••
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Providence Saint Vincent Medical Center
RECRUITINGPortland, Oregon, 97225, United States
Contact Email: •••••@•••••
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Providence Willamette Falls Medical Center
RECRUITINGOregon City, Oregon, 97045, United States
Contact Email: •••••@•••••
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Regions Hospital
RECRUITINGSaint Paul, Minnesota, 55101, United States
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Riverside Methodist Hospital
RECRUITINGColumbus, Ohio, 43214, United States
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Rush-Copley Medical Center
RECRUITINGAurora, Illinois, 60504, United States
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Saint Vincent Hospital Cancer Center Green Bay
RECRUITINGGreen Bay, Wisconsin, 54301, United States
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Saint Vincent Hospital Cancer Center at Oconto Falls
RECRUITINGOconto Falls, Wisconsin, 54154, United States
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Saint Vincent Hospital Cancer Center at Saint Mary's
RECRUITINGGreen Bay, Wisconsin, 54303, United States
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Saint Vincent Hospital Cancer Center at Sheboygan
RECRUITINGSheboygan, Wisconsin, 53081, United States
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Saint Vincent Hospital Cancer Center at Sturgeon Bay
RECRUITINGSturgeon Bay, Wisconsin, 54235-1495, United States
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Sheboygan Physicians Group
RECRUITINGSheboygan, Wisconsin, 53081, United States
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Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
Contact Email: •••••@•••••
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Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
Contact Email: •••••@•••••
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
Contact Email: •••••@•••••
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Smilow Cancer Hospital Care Center - Guilford
RECRUITINGGuilford, Connecticut, 06437, United States
Contact Email: •••••@•••••
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Smilow Cancer Hospital Care Center at Greenwich
RECRUITINGGreenwich, Connecticut, 06830, United States
Contact Email: •••••@•••••
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Smilow Cancer Hospital Care Center at Long Ridge
RECRUITINGStamford, Connecticut, 06902, United States
Contact Email: •••••@•••••
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Smilow Cancer Hospital Care Center at Saint Francis
RECRUITINGHartford, Connecticut, 06105, United States
Contact Email: •••••@•••••
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Smilow Cancer Hospital Care Center-Trumbull
RECRUITINGTrumbull, Connecticut, 06611, United States
Contact Email: •••••@•••••
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Smilow Cancer Hospital-Derby Care Center
RECRUITINGDerby, Connecticut, 06418, United States
Contact Email: •••••@•••••
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Thomas Jefferson University Hospital
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••
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UC Irvine Health/Chao Family Comprehensive Cancer Center
RECRUITINGOrange, California, 92868, United States
Contact Email: •••••@•••••
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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
RECRUITINGIrvine, California, 92612, United States
Contact Email: •••••@•••••
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UI Health Care Mission Cancer and Blood - Ankeny Clinic
RECRUITINGAnkeny, Iowa, 50023, United States
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UI Health Care Mission Cancer and Blood - Des Moines Clinic
RECRUITINGDes Moines, Iowa, 50309, United States
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UI Health Care Mission Cancer and Blood - Laurel Clinic
RECRUITINGDes Moines, Iowa, 50314, United States
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UI Health Care Mission Cancer and Blood - Waukee Clinic
RECRUITINGWaukee, Iowa, 50263, United States
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UI Health Care Mission Cancer and Blood - West Des Moines Clinic
RECRUITINGClive, Iowa, 50325, United States
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UM Sylvester Comprehensive Cancer Center at Aventura
RECRUITINGAventura, Florida, 33180, United States
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UM Sylvester Comprehensive Cancer Center at Coral Gables
RECRUITINGCoral Gables, Florida, 33146, United States
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UM Sylvester Comprehensive Cancer Center at Coral Springs
RECRUITINGCoral Springs, Florida, 33065, United States
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UM Sylvester Comprehensive Cancer Center at Deerfield Beach
RECRUITINGDeerfield Beach, Florida, 33442, United States
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UM Sylvester Comprehensive Cancer Center at Hollywood
RECRUITINGHollywood, Florida, 33021, United States
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UM Sylvester Comprehensive Cancer Center at Kendall
RECRUITINGMiami, Florida, 33176, United States
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UM Sylvester Comprehensive Cancer Center at Plantation
RECRUITINGPlantation, Florida, 33324, United States
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United Hospital
RECRUITINGSaint Paul, Minnesota, 55102, United States
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University of Arizona Cancer Center-North Campus
RECRUITINGTucson, Arizona, 85719, United States
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University of Illinois
RECRUITINGChicago, Illinois, 60612, United States
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Kansas Hospital-Westwood Cancer Center
RECRUITINGWestwood, Kansas, 66205, United States
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University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITINGMiami, Florida, 33136, United States
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University of Miami Sylvester Comprehensive Cancer Center at Sole Mia
RECRUITINGNorth Miami, Florida, 33181, United States
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University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Email: •••••@•••••
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
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University of Pennsylvania/Abramson Cancer Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Email: •••••@•••••
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University of Rochester
RECRUITINGRochester, New York, 14642, United States
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University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
RECRUITINGMadison, Wisconsin, 53718, United States
Contact Email: •••••@•••••
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University of Wisconsin Carbone Cancer Center - University Hospital
RECRUITINGMadison, Wisconsin, 53792, United States
Contact Email: •••••@•••••
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Walter Reed National Military Medical Center
RECRUITINGBethesda, Maryland, 20889-5600, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Email: •••••@•••••
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Wayne State University/Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
Contact Email: •••••@•••••
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Weisberg Cancer Treatment Center
RECRUITINGFarmington Hills, Michigan, 48334, United States
Contact Email: •••••@•••••
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Yale University
RECRUITINGNew Haven, Connecticut, 06520, United States
Contact Email: •••••@•••••
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Yale-New Haven Hospital North Haven Medical Center
RECRUITINGNorth Haven, Connecticut, 06473, United States
Contact Email: •••••@•••••
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