New study tailors amyloidosis therapy based on genetic marker

NCT ID NCT06192979

First seen Mar 14, 2026 · Last updated May 01, 2026 · Updated 5 times

Summary

This study tests a personalized approach for people newly diagnosed with AL amyloidosis who have a specific genetic change called t(11;14). All participants start with a standard three-drug combination. If their blood responds quickly within 7 days, they continue that treatment; if not, they switch to a different combination that includes a targeted drug. The goal is to improve the chance of complete blood and organ recovery. About 41 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital

    RECRUITING

    Beijing, Beijing Municipality, 101118, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Capital Medical University Affiliated Fuxing Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100045, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chinese PLA Eastern Theater General Hospital

    RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking University People's Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100044, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Qingdao Municipal Hospital

    RECRUITING

    Qingdao, Shandong, 266011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xi'an Jiao Tong University

    RECRUITING

    Xi’an, Shanxi, 710061, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.