New Clot-Busting device could offer quick relief for lung blockages

NCT ID NCT06672510

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called the Akura Thrombectomy System, which is threaded through a blood vessel to mechanically remove clots from the lung arteries. It involves 118 adults with acute pulmonary embolism (symptoms for 14 days or less) who have a clot in a main or lobar artery and signs of heart strain. The goal is to see if the device safely restores blood flow and reduces strain on the heart.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Akura Thrombectomy System (a catheter-based device to mechanically remove blood clots)

What this could lead to

If it works, this could provide a new, less invasive option to quickly remove dangerous clots from the lungs, potentially reducing heart strain and improving survival.

What could go wrong

This is an early-stage, single-arm study with only 118 participants, so results may not apply to everyone. Risks include bleeding, vessel injury, or the device not working as expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced Heart & Vein (ClinRe-001-001)

    RECRUITING

    Thornton, Colorado, 80023, United States

    Contact

    Contact Email: •••••@•••••

  • Centracare Heart & Vascular Center

    RECRUITING

    Saint Cloud, Minnesota, 56301, United States

    Contact

    Contact Email: •••••@•••••

  • Columbia University Medical Center

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Email: •••••@•••••

  • Cumc/Nyph

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Email: •••••@•••••

  • Hartford Healthcare

    RECRUITING

    Hartford, Connecticut, 06102, United States

    Contact

    Contact Email: •••••@•••••

  • Jacksonville Memorial (HCA)

    ACTIVE_NOT_RECRUITING

    Jacksonville, Florida, 32216, United States

  • Los Robles Regional Medical Center

    RECRUITING

    Thousand Oaks, California, 91360, United States

    Contact Email: •••••@•••••

    Contact

  • Manatee Hospital / Nova Clinical Research Center

    ACTIVE_NOT_RECRUITING

    Bradenton, Florida, 32808, United States

  • Methodist San Antonio (HCA)

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact

    Contact Email: •••••@•••••

  • ProMedica Toledo Hospital

    RECRUITING

    Toledo, Ohio, 43606, United States

    Contact

    Contact Email: •••••@•••••

  • Tallahasse Memorial Hospital

    RECRUITING

    Tallahassee, Florida, 32308, United States

    Contact

    Contact Email: •••••@•••••

    Contact

  • Tristar Centennial Medical Center

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

    Contact Email: •••••@•••••