New Clot-Busting device could offer quick relief for lung blockages

NCT ID NCT06672510

Recruiting now Disease control Sponsor: Akura Medical Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called the Akura Thrombectomy System, which is threaded through a blood vessel to mechanically remove clots from the lung arteries. It involves 118 adults with acute pulmonary embolism (symptoms for 14 days or less) who have a clot in a main or lobar artery and signs of heart strain. The goal is to see if the device safely restores blood flow and reduces strain on the heart.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Akura Thrombectomy System (a catheter-based device to mechanically remove blood clots)
What this could lead to: If it works, this could provide a new, less invasive option to quickly remove dangerous clots from the lungs, potentially reducing heart strain and improving survival.
What could go wrong: This is an early-stage, single-arm study with only 118 participants, so results may not apply to everyone. Risks include bleeding, vessel injury, or the device not working as expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PULMONARY EMBOLISM ACUTE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY EMBOLISM ACUTE

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••
Contact

Email: •••••@•••••

Locations

Advanced Heart & Vein (ClinRe-001-001)
RECRUITING

Thornton, Colorado, 80023, United States
Centracare Heart & Vascular Center
RECRUITING

Saint Cloud, Minnesota, 56301, United States
Columbia University Medical Center
NOT_YET_RECRUITING

New York, New York, 10032, United States
Cumc/Nyph
NOT_YET_RECRUITING

New York, New York, 10032, United States
Hartford Healthcare
RECRUITING

Hartford, Connecticut, 06102, United States
Jacksonville Memorial (HCA)
ACTIVE_NOT_RECRUITING

Jacksonville, Florida, 32216, United States
Los Robles Regional Medical Center
RECRUITING

Thousand Oaks, California, 91360, United States
Manatee Hospital / Nova Clinical Research Center
ACTIVE_NOT_RECRUITING

Bradenton, Florida, 32808, United States
Methodist San Antonio (HCA)
RECRUITING

San Antonio, Texas, 78229, United States
ProMedica Toledo Hospital
RECRUITING

Toledo, Ohio, 43606, United States
Tallahasse Memorial Hospital
RECRUITING

Tallahassee, Florida, 32308, United States
Tristar Centennial Medical Center
RECRUITING

Nashville, Tennessee, 37203, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.