Asthma breakthrough? study compares adding dupilumab vs. upping inhaler dose

NCT ID NCT06572228

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Sep 30, 2025 · Last updated May 12, 2026 · Updated 30 times

Summary

This study looks at 250 adults with asthma that is not well controlled by their current medium-dose inhaler. Researchers want to see if adding a drug called dupilumab to the usual inhaler works better than simply increasing the inhaler dose. The goal is to reduce severe asthma attacks and improve breathing, while also tracking side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

ALL-MED Specjalistyczna Opieka Medyczna Medyczny Instytut Badawczy
ACTIVE_NOT_RECRUITING

Wroclaw, PL-53-201, Poland
Allergy & Asthma Care of Waco
ACTIVE_NOT_RECRUITING

Waco, Texas, 76712, United States
Allergy & Asthma Specialists, P.S.C.
ACTIVE_NOT_RECRUITING

Owensboro, Kentucky, 42301, United States
Allergy Asthma and Clinical Research Center
ACTIVE_NOT_RECRUITING

Oklahoma City, Oklahoma, 73120, United States
Allergy Clinic NZOZ Homeo Medicus
ACTIVE_NOT_RECRUITING

Bialystok, Podlaskie Voivodeship, 15-687, Poland
Allergy and Asthma Center of Minnesota
WITHDRAWN

Maplewood, Minnesota, 55109, United States
Allianz Research Institute
ACTIVE_NOT_RECRUITING

Westminster, California, 92683, United States
Allianze pulmonary Research
WITHDRAWN

Guaynabo, 00968, Puerto Rico
Antelope Valley Clinical Trials
ACTIVE_NOT_RECRUITING

Lancaster, California, 93534, United States
Ark Clinical Research, LLC
ACTIVE_NOT_RECRUITING

Long Beach, California, 90815, United States
Asthma and Allergy Center of Chicago
ACTIVE_NOT_RECRUITING

River Forest, Illinois, 60305, United States
Baylor College of Medicine - Section of Pulmonary and Critical Care
ACTIVE_NOT_RECRUITING

Houston, Texas, 77030, United States
Bensch Clinical Research
ACTIVE_NOT_RECRUITING

Stockton, California, 95207, United States
Bluegrass Allergy Research
ACTIVE_NOT_RECRUITING

Lexington, Kentucky, 40509, United States
Centrum Medycyny Oddechowej Mroz SJ
ACTIVE_NOT_RECRUITING

Bialystok, Podlaskie Voivodeship, 15-044, Poland
Centrum Medyczne All-Med
ACTIVE_NOT_RECRUITING

Krakow, Lesser Poland Voivodeship, 30-033, Poland
Certified Research Associates
ACTIVE_NOT_RECRUITING

Cortland, New York, 13045, United States
Childrens Hospital of Orange County Main Campus
RECRUITING

Orange, California, 92868, United States
Cincinnati Childrens Hospital and Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States
Clinical Research Associates of Central PA
COMPLETED

DuBois, Pennsylvania, 15801, United States
Clinical Research Institute, Inc.
ACTIVE_NOT_RECRUITING

Minneapolis, Minnesota, 55402, United States
Clinical Site Partners, LLC DBA Flourish Research
ACTIVE_NOT_RECRUITING

Winter Park, Florida, 32789, United States
Clinique de Specialisee en Allergie de la Capitale
ACTIVE_NOT_RECRUITING

Québec, G1V 4W2, Canada
Copenhagen University Hospital - Hvidovre
WITHDRAWN

Hvidovre, Capital Region, 2650, Denmark
Dharma MD PA d/b/a Southwest Family Medicine Associates
ACTIVE_NOT_RECRUITING

Dallas, Texas, 75235, United States
Diamond Clinic sp zoo
ACTIVE_NOT_RECRUITING

Krakow, Malopolska, 31-559, Poland
Dr. Syed Anees Medicine Professional Corporation
ACTIVE_NOT_RECRUITING

Windsor, Ontario, N8X 1T3, Canada
Dynamic Drug Advancement Ltd.
ACTIVE_NOT_RECRUITING

Ajax, Ontario, L1S 2J5, Canada
Endeavor Health, Skokie Campus
ACTIVE_NOT_RECRUITING

Skokie, Illinois, 60077, United States
European Trial Group (ETG) Warsaw
RECRUITING

Warsaw, Mazovian, 02-677, Poland
Evidence Based Medical Educator Inc.
ACTIVE_NOT_RECRUITING

Toronto, Ontario, M5G 1E2, Canada
Family Allergy and Asthma Research Institute
RECRUITING

Louisville, Kentucky, 40217, United States
Florida Lung, Asthma and Sleep Specialists (FLASS) - Celebration
ACTIVE_NOT_RECRUITING

Kissimmee, Florida, 34746, United States
Fundacion de Investigacion (FDI) Clinical Research
WITHDRAWN

San Juan, 00927, Puerto Rico
Henderson Clinical Trials
ACTIVE_NOT_RECRUITING

Henderson, Nevada, 89052, United States
Henry Ford Hospital
ACTIVE_NOT_RECRUITING

Detroit, Michigan, 48202, United States
IKF Pneumologie Frankfurt GmbH & Co KG
ACTIVE_NOT_RECRUITING

Frankfurt am Main, Hesse, 60596, Germany
IKF Pneumologie GmbH & Co. KG
ACTIVE_NOT_RECRUITING

Mainz, 55128, Germany
Inova Fairfax Hospital
COMPLETED

Falls Church, Virginia, 22042, United States
Inspiration Research Limited
ACTIVE_NOT_RECRUITING

Toronto, Ontario, M5T 3A9, Canada
Institut Universitare de Cardiologie et de Pneumologie de Quebec (IUCPQ) - Universite Laval
RECRUITING

Québec, G1V 4G5, Canada
Integrated Research of Inland, Inc.
COMPLETED

Upland, California, 91786, United States
Intermountain Medical Center - Murray (Pulmonary Medicine)
RECRUITING

Murray, Utah, 84107, United States
KPPK Studienzentrum
ACTIVE_NOT_RECRUITING

Koblenz, Rhineland-Palatinate, 56068, Germany
Kern Research, Inc
ACTIVE_NOT_RECRUITING

Bakersfield, California, 93301, United States
LMU University Hospital Munich
ACTIVE_NOT_RECRUITING

Munich, Bavaria, 81377, Germany
Lekarze Specjaliści Małolepszy i Partnerzy
ACTIVE_NOT_RECRUITING

Wroclaw, 54239, Poland
Lung Sleep Research Institute
ACTIVE_NOT_RECRUITING

North Richland Hills, Texas, 76180, United States
Lungenpraxis Hohenzollerndamm RCMS
ACTIVE_NOT_RECRUITING

Berlin, 10717, Germany
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Metroplex Pulmonary and Sleep Center, PA
ACTIVE_NOT_RECRUITING

McKinney, Texas, 75069, United States
Michał Bogacki - DOBROSTAN
ACTIVE_NOT_RECRUITING

Wroclaw, Lower Silesian Voivodeship, 53301, Poland
Michigan Medicine
ACTIVE_NOT_RECRUITING

Ann Arbor, Michigan, 48109, United States
Modena Allergy & Asthma, Inc.
ACTIVE_NOT_RECRUITING

La Jolla, California, 92037, United States
Montana Medical Research
ACTIVE_NOT_RECRUITING

Missoula, Montana, 59808, United States
National Jewish Health
ACTIVE_NOT_RECRUITING

Denver, Colorado, 80206, United States
New York Medical College
RECRUITING

Hawthorne, New York, 10532, United States
Newport Native Md, Inc.
ACTIVE_NOT_RECRUITING

Newport Beach, California, 92663, United States
Northwell Health at ENT & Allergy Associates
RECRUITING

New York, New York, 10016, United States
Northwestern University
WITHDRAWN

Chicago, Illinois, 60611, United States
POIS Sachsen GmbH iG
ACTIVE_NOT_RECRUITING

Leipzig, 04347, Germany
PRCCI Clinical Research Center
ACTIVE_NOT_RECRUITING

San Juan, 00927, Puerto Rico
Paul A. Shapero, M.D.
ACTIVE_NOT_RECRUITING

Bangor, Maine, 04401, United States
Praxis fur Pneumologie am Duako
RECRUITING

Augsburg, Bavaria, 86150, Germany
Premier Pulmonary Critical Care and Sleep Medicine
ACTIVE_NOT_RECRUITING

Denison, Texas, 75020, United States
Pulmonology Associates Inc.
RECRUITING

Wynnewood, Pennsylvania, 19096, United States
Raffi Tachdjian MD, Inc.
COMPLETED

Santa Monica, California, 90404, United States
Riviera Allergy Medical Center
WITHDRAWN

Redondo Beach, California, 90277, United States
Rochester Regional Health - Alexander Park - Allergy, Immunology & Rheumatology
ACTIVE_NOT_RECRUITING

Rochester, New York, 14607, United States
Sneeze Wheeze and Itch Associates
ACTIVE_NOT_RECRUITING

Normal, Illinois, 61761, United States
South Texas Allergy & Asthma Medical Professionals (STAAMP) Research
ACTIVE_NOT_RECRUITING

San Antonio, Texas, 78229, United States
St Francis Medical Institute
ACTIVE_NOT_RECRUITING

Clearwater, Florida, 33765, United States
Texas Children's Hospital
ACTIVE_NOT_RECRUITING

Houston, Texas, 77030, United States
The Asthma and Allergy Center
ACTIVE_NOT_RECRUITING

Bellevue, Nebraska, 68123, United States
The Lung Centre at Vancouver General Hospital
ACTIVE_NOT_RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada
Treasure Valley Medical Research
ACTIVE_NOT_RECRUITING

Boise, Idaho, 83706, United States
University of Kansas Medical Center
ACTIVE_NOT_RECRUITING

Kansas City, Kansas, 66160, United States
University of Pittsburgh Asthma and Environmental Health Lung Institute
ACTIVE_NOT_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Uniwersyteckie Centrum Kliniczne, Budynek Centrum Medycyny Nieinwazyjnej
ACTIVE_NOT_RECRUITING

Gdansk, Pomeranian Voivodeship, 80-214, Poland
Vancouver Clinic
WITHDRAWN

Vancouver, Washington, 98664, United States
Vejle Sygehus
ACTIVE_NOT_RECRUITING

Vejle, Region Syddanmark, 7100, Denmark
Velocity Clinical Research Lubeck GmbH (Formerly KLB Gesundheitsforschung Lübeck GmbH)
ACTIVE_NOT_RECRUITING

Lübeck, Schleswig-Holstein, 23552, Germany
Washington University School of Medicine
ACTIVE_NOT_RECRUITING

St Louis, Missouri, 63119, United States
Western Sky Medical Research
ACTIVE_NOT_RECRUITING

El Paso, Texas, 79912, United States

Conditions

Explore the condition pages connected to this study.

ASTHMA