Cure My Disease

Don't miss your cure!

 Log in / Sign up

AI vs. experts: can machines master Parkinson's motor scoring?

NCT ID NCT05906719

Knowledge-focused Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This trial tests whether a machine vision system can accurately rate the motor symptoms of Parkinson's disease, as measured by the MDS-UPDRS Part III scale. Researchers will record videos of patients performing standardized tasks and use machine learning to develop an AI rating model. The AI's scores will be compared against expert consensus ratings to see if it can match or approach human-level accuracy. The study involves about 1,679 participants with parkinsonism, aged 20 to 80.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
video recording of patients performing motor tasks
What this could lead to
If successful, this could lead to an automated, objective tool for assessing Parkinson's motor symptoms, potentially improving access to consistent evaluations.
What could go wrong
The AI model may not match the accuracy of human experts, and its performance could vary across different patient populations or settings. Early-stage research with potential for bias.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,679 people

The number who actually took part.

Started

Mar 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

In this study, participants are mainly recruited from the Department of Neurology at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, as well as from movement disorder clinics at 7 other centers. Participants are enrolled through outpatient assessment and screening. Two specialists in movement disorders independently diagnosed participants as having "Parkinsonism". In cases where there is a diagnostic disagreement, the Movement Disorder Specialist Group at the Department of Neurology, Ruijin Hospital collectively discusses and makes the decision.

Ages

20 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meeting the diagnostic criteria for Parkinsonism established by the International Movement Disorder Society: having bradykinesia, and meeting at least one of the two criteria for resting tremor or muscle rigidity * 20 to 80 years old * Good compliance, voluntarily joining the study, and able to sign an informed consent form or have it signed by a legal representative Exclusion Criteria: * Significant cognitive impairment (MMSE ≤ 23) * Unable to sign written informed consent or unable to complete the trial due to other reasons * Other situations in which the researcher deems the participant unsuitable for this study * Participation in other clinical trials

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Machine learning are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

parkinsonian disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Machine learning Parkinsonian disorders

Contacts and locations

Locations

  • Beijing Hospital, Neurology Department

    Beijing, Beijing Municipality, 100730, China

  • Center for Movement Disorders, Department of Neurology, Beijing Tiantan Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100050, China

  • Department of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215004, China

  • Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200025, China

  • Department of Neurology, Fujian Medical University Union Hospital

    Fuzhou, Fujian, 350001, China

  • Department of Neurology, Guangdong Neuroscience Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences

    Guangzhou, Guangdong, 510080, China

  • Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Department of Neurology, West China Hospital, Sichuan University

    Chengdu, Sichuan, 610044, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.