AI could help endoscopists catch stomach cancer earlier
NCT ID NCT07551466
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing an artificial intelligence (AI) model designed to help doctors detect early gastric (stomach) cancer during endoscopy. The AI combines images from standard and enhanced endoscopy with patient data to improve accuracy and explain its reasoning. Researchers will enroll 100 adults with suspicious stomach lesions to see how well the AI performs compared to standard diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this AI tool could help endoscopists detect early gastric cancer more reliably, potentially leading to earlier treatment and better outcomes.
- What could go wrong
- This is an observational study with only 100 participants, so the AI model may not perform as well in larger, more diverse groups. It is not yet ready for widespread clinical use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with suspected gastric lesions who underwent endoscopic examination and endoscopic submucosal dissection (ESD), with available white-light imaging (WLI), magnifying endoscopy with narrow-band imaging (ME-NBI), and histopathological diagnosis at participating centers.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Suspicious gastric lesions identified on white-light imaging (WLI) * Preoperative biopsy indicating precancerous lesions (dysplasia or intraepithelial neoplasia) or adenocarcinoma, with preoperative magnifying endoscopy with narrow-band imaging (ME-NBI) performed * Patients meeting the absolute indications for endoscopic submucosal dissection (ESD) and who underwent ESD Exclusion Criteria: * Non-adenocarcinoma histological types (e.g., lymphoma) * Patients who did not undergo ME-NBI examination or did not receive ESD * Lesions invading the muscularis propria or deeper layers * Missing or indeterminate postoperative histopathological results
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The First Affiliated Hospital of Soochow University
RECRUITINGSuzhou, China
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Other studies related to the condition(s) this trial covers.
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- Stomach bug clues: can infection patterns forecast early cancer behavior?
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- New Dual-Scope surgery shows promise for early stomach cancer
- New laser probe could spot stomach cancer earlier than biopsy