AI-Powered heart check could spot silent disease in minutes

NCT ID NCT06891222

Ongoing Diagnosis Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining an AI-enhanced electrocardiogram (ECG) with a focused heart ultrasound can better detect structural heart disease in people without symptoms. About 2,705 adults with no known heart problems will get an AI-ECG, and if it flags a concern, they'll also get a quick ultrasound. The goal is to see if this approach catches more cases of hidden heart conditions like weak heart muscle or narrowed valves.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AI-ECG and focused cardiac ultrasound
What this could lead to: If successful, this could make heart disease screening faster and easier, catching problems early with just an ECG and a quick ultrasound.
What could go wrong: This is an early-stage screening study, not a treatment trial. The AI may not be accurate enough, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC DISEASE

Contacts and locations

Locations

Mayo Clinic

Rochester, Minnesota, 55905, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.