AI boosts colonoscopy accuracy in massive VA trial

NCT ID NCT05888623

Completed Diagnosis Sponsor: VA Puget Sound Health Care System Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large study tested whether an artificial intelligence system (GI Genius) can help doctors spot precancerous polyps during colonoscopy. Over 334,000 veterans at VA hospitals across the U.S. took part. Some hospitals used the AI device, while others did not. Researchers compared how often adenomas (precancerous growths) were found in each group. The goal is to see if AI improves detection and could lead to fewer colorectal cancers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Computer-assisted detection device (GI Genius Intelligent Endoscopy Module)
What this could lead to: If successful, this could show that AI helps doctors find more precancerous polyps during colonoscopy, potentially reducing colorectal cancer rates.
What could go wrong: The study is observational and compares hospitals, not individual patients, so results may be influenced by other factors. AI might also increase false positives or procedure time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adenoma colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL NEOPLASMS

Contacts and locations

Locations

VA Puget Sound Health Care System

Seattle, Washington, 98108, United States

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