New shot aims to silence hepatitis b virus for good

NCT ID NCT07630727

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests an injection called AHB-171 in 138 people with chronic hepatitis B. The goal is to see if it can lower hepatitis B surface antigen and viral DNA to very low levels, potentially leading to a functional cure. Participants include those who have never been treated and those already on antiviral therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AHB-171 injection

What this could lead to

If successful, this could point toward a functional cure for chronic hepatitis B, where the virus is suppressed to very low or undetectable levels without lifelong medication.

What could go wrong

This is an early Phase 2 trial with only 138 participants, so results may not apply to everyone. The treatment may not achieve lasting viral suppression, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Bronchiolitis Obliterans Syndrome chronic hepatitis B virus infection hepatitis B virus infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AusperBio Investigational Site

    Jilin City, Jilin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••