New hope for tough-to-treat pancreatic cancer? drug combo enters phase 2 trial

NCT ID NCT05632328

First seen Apr 17, 2026 · Last updated Jun 13, 2026 · Updated 9 times

Summary

This study tests a combination of two experimental drugs (AGEN1423 and botensilimab) with or without standard chemotherapy in people with advanced pancreatic cancer that has worsened after at least one prior treatment. The goal is to see if the combination can shrink tumors or slow the disease. About 24 adults are taking part, receiving treatment for up to 2 years with follow-up for 1 year after.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

Conditions

Explore the condition pages connected to this study.