Sound waves smash heart artery calcium in new trial

NCT ID NCT07512206

First seen Apr 10, 2026 · Last updated Jun 20, 2026 · Updated 10 times

Summary

This study tests a new device called the Shockwave C2 Aero, which uses sound waves to break up calcium deposits in heart arteries before placing a stent. About 200 people with coronary artery disease will be enrolled across 8 U.S. sites. The goal is to see if the device works safely and effectively in real-world settings.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor Scott & White Health - The Heart Hospital Plano

    Plano, Texas, 75093, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Good Samaritan University Hospital

    West Islip, New York, 11795, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henry Ford St. John Hospital

    Detroit, Michigan, 48236, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jersey Shore University Medical Center

    Neptune City, New Jersey, 07753, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Los Robles Regional Medical Center

    Thousand Oaks, California, 91360, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St Francis Hospital & Heart Center

    Roslyn, New York, 11576, United States

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Valley Hospital

    Paramus, New Jersey, 07652, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • WellSpan Health, York Hospital

    York, Pennsylvania, 17403, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Shockwave C2 Aero Coronary Intravascular Lithotripsy (IVL) System (a device that uses sound waves to break up calcium in heart arteries)

What this could lead to

If successful, this device could offer a safer, more effective way to treat heavily calcified coronary arteries, potentially reducing complications and improving long-term heart health.

What could go wrong

This is a small, early-stage study (200 people) without a comparison group, so results may not apply to everyone. Risks include artery damage, heart attack, or the device failing to work as intended.

Conditions

The condition(s) this trial relates to.

coronary artery disorder coronary atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.