Major trial tests new drug combo against standard hodgkin lymphoma treatment

NCT ID NCT01712490

Completed Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

Summary

This large, completed study compared two different chemotherapy combinations for adults with newly diagnosed, advanced Hodgkin lymphoma. Over 1,300 patients were randomly assigned to receive either the standard treatment (ABVD) or a newer regimen (A+AVD) that included a targeted drug called brentuximab vedotin. The main goal was to see which treatment was better at keeping the cancer from progressing or coming back.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Birmingham, Alabama, United States
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Gilbert, Arizona, United States
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Tucson, Arizona, United States
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Burbank, California, United States
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Duarte, California, United States
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Fresno, California, United States
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Fullerton, California, United States
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La Jolla, California, United States
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Long Beach, California, United States
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Los Angeles, California, United States
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Sacramento, California, United States
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San Luis Obispo, California, United States
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Santa Barbara, California, United States
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Santa Monica, California, United States
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Stanford, California, United States
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Colorado Springs, Colorado, United States
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Denver, Colorado, United States
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Lonetree, Colorado, United States
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Washington D.C., District of Columbia, United States
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Fort Myers, Florida, United States
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Jacksonville, Florida, United States
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Miami, Florida, United States
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Orlando, Florida, United States
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Lawrenceville, Georgia, United States
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Chicago, Illinois, United States
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Maywood, Illinois, United States
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Niles, Illinois, United States
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Zion, Illinois, United States
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Fort Wayne, Indiana, United States
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Goshen, Indiana, United States
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Indianapolis, Indiana, United States
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Iowa City, Iowa, United States
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Fairway, Kansas, United States
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Baltimore, Maryland, United States
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Bethesda, Maryland, United States
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Boston, Massachusetts, United States
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Ann Arbor, Michigan, United States
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Detroit, Michigan, United States
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Minneapolis, Minnesota, United States
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Rochester, Minnesota, United States
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Springfield, Missouri, United States
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St Louis, Missouri, United States
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Lincoln, Nebraska, United States
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Omaha, Nebraska, United States
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Las Vegas, Nevada, United States
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Basking Ridge, New Jersey, United States
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Hackensack, New Jersey, United States
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Morristown, New Jersey, United States
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Albuquerque, New Mexico, United States
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Albany, New York, United States
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Commack, New York, United States
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New York, New York, United States
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Rochester, New York, United States
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Rockville Centre, New York, United States
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The Bronx, New York, United States
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Charlotte, North Carolina, United States
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Raleigh, North Carolina, United States
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Bismarck, North Dakota, United States
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Cincinnati, Ohio, United States
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Columbus, Ohio, United States
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Oklahoma City, Oklahoma, United States
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Eugene, Oregon, United States
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Hershey, Pennsylvania, United States
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Philadelphia, Pennsylvania, United States
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Charleston, South Carolina, United States
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Greenville, South Carolina, United States
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Chattanooga, Tennessee, United States
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Knoxville, Tennessee, United States
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Nashville, Tennessee, United States
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Austin, Texas, United States
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Dallas, Texas, United States
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Houston, Texas, United States
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San Antonio, Texas, United States
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Tyler, Texas, United States
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Salt Lake City, Utah, United States
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Fairfax, Virginia, United States
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Richmond, Virginia, United States
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Kennewick, Washington, United States
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Seattle, Washington, United States
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Vancouver, Washington, United States
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Yakima, Washington, United States
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Morgantown, West Virginia, United States
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Milwaukee, Wisconsin, United States
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Kingswood, New South Wales, Australia
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St Leonards, New South Wales, Australia
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Westmead, New South Wales, Australia
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South Brisbane, Queensland, Australia
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Bedford Park, South Australia, Australia
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Hobart, Tasmania, Australia
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East Melbourne, Victoria, Australia
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Geelong, Victoria, Australia
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Heidelberg, Victoria, Australia
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Parkville, Victoria, Australia
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Perth, Western Australia, Australia
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Antwerp, Belgium
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Bruges, Belgium
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Ghent, Belgium
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Salvador, Estado de Bahia, Brazil
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Curitiba, Paraná, Brazil
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Porto Alegre, Rio Grande do Sul, Brazil
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Santo André, São Paulo, Brazil
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Rio de Janeiro, Brazil
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São Paulo, Brazil
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Edmonton, Alberta, Canada
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Vancouver, British Columbia, Canada
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Winnipeg, Manitoba, Canada
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Halifax, Nova Scotia, Canada
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Toronto, Ontario, Canada
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Montreal, Quebec, Canada
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Saskatoon, Saskatchewan, Canada
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Hradec Králové, Czechia
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Prague, Czechia
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Aalborg, Denmark
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Aarhus C, Denmark
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Copenhagen, Denmark
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Odense C, Denmark
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Roskilde, Denmark
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Argenteuil, Cedex, France
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La Tronche, France
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Limoges, France
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Paris, France
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Lai Chi Kok, Kowloon, Hong Kong
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Hong Kong, Hong Kong
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Tuenmen, Hong Kong
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Budapest, Hungary
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Debrecen, Hungary
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Győr, Hungary
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Pécs, Hungary
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Szeged, Hungary
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Modena, Emilia-Romagna, Italy
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Rome, Lazio, Italy
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Alessandria, Italy
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Bologna, Italy
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Cagliari, Italy
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Cuneo, Italy
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Genova, Italy
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Milan, Italy
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Naples, Italy
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Rionero in Volture, Italy
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Rome, Italy
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Rozzano, Italy
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Torrette Di Ancona, Italy
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Higashiku, Fukuoka, Japan
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Minamiku, Fukuoka-city, Japan
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Minamiku, Hiroshima-city, Japan
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Shōwamachi, Maebashi-city, Japan
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Chikusa-ku, Nagoya, Japan
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Suita, Osaka, Japan
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Aoba-ku, Sendai-city, Japan
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Chūōku, Japan
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Isehara-shi, Japan
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Kōtoku, Japan
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Bergen, Norway
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Oslo, Norway
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Gdansk, Poland
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Katowice, Poland
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Krakow, Poland
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L0dz, Poland
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Olsztyn, Poland
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Warsaw, Poland
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Wroclaw, Poland
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Ufa, Bashkortostan Republic, Russia
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Saint Petersburg, Poselok Pesochny, Russia
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Kazan', Republic Tatrstan, Russia
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Moscow, Russia
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Moskva, Russia
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Saint Petersburg, Russia
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Johannesburg, Gauteng, South Africa
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Pretoria, Gauteng, South Africa
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eManzimtoti, KwaZulu-Natal, South Africa
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Bloemfontein, South Africa
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Cape Town, South Africa
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Goyang-si, Gyeonggi-do, South Korea
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Hwasun-gun, Jeollanam-do, South Korea
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Seocho-gu, Seoul, South Korea
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Busan, South Korea
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Daegu, South Korea
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Incheon, South Korea
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Jeonju, South Korea
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Seoul, South Korea
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Badalona, Spain
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Barcelona, Spain
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Marbella, Spain
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Pamplona, Spain
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Salamanca, Spain
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Santiago de Compostela, Spain
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Valencia, Spain
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Changhua, Taiwan
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Chiayi County 613, Taiwan
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Tainan, Taiwan
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Taipei, Taiwan
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Taoyuan, Taiwan
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Ankara, Turkey (Türkiye)
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Istanbul, Turkey (Türkiye)
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Samsun, Turkey (Türkiye)
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Truro, Cornwall, United Kingdom
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Aberdeen, Scotland, United Kingdom
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Glasgow, Scotland, United Kingdom
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Sutton, Surrey, United Kingdom
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Cardiff, Wales, United Kingdom
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Birmingham, United Kingdom
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Canterbury, United Kingdom
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Exeter, United Kingdom
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Inverness, United Kingdom
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Leicester, United Kingdom
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Lincoln, United Kingdom
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Liverpool, United Kingdom
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London, United Kingdom
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Manchester, United Kingdom
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Norfolk, United Kingdom
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Northwood, United Kingdom
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Nottingham, United Kingdom
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Oxford, United Kingdom
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Romford, United Kingdom
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Southampton, United Kingdom

Conditions

Explore the condition pages connected to this study.

HODGKIN LYMPHOMA